Intensive therapy of severe complications of influenza

Abstract

Definition of risk factors and clinical characteristics of heavy complications of influenza for working out of criteria of polymodal intensive therapy and resuscitation was the work purpose. Results of linical supervision by 114 sick heavy form of influenza with pulmonary and extra pulmonary complications are presented. All patients suffered from virus pneumonia and sharp defeat of lungs /sharp respirator distress-syndrome (OPL/ORDS). Pulmonary complications included bacterial (85, 96 %) and micotic (2, 63 %) pneumonia, thrombosis of legoch arteries (19,29 %), the sharp respiratory insufficiency, caused by the polyneuropathy of a critical condition of the patient (18,42 %), the exssudative pleuritis (9,65 %), spontaneous pheumothorax (4,39 %), spontaneous pheumomediastinum (2,69 %). Extra pulmonary complications concerned the swell of brain at 100 % of patients, including, with development of a brain coma (26,32 %), sepsis (85,96 %), including, with development of septic shock (68,42 %), syndrome of disseminated intravenous coagulation (49,12 %), multyorgan insufficiency (56,14 %), sharp heavy miocarditis (22,81 %), sharp nephritic insufficiency (18,42 %), sharp hepatic insufficiency (10,52 %). Early development of pathophysiological processes (the expressed infringements of a gas exchange and an acid-base condition, a secondary immunodeficiency, heamodynamical insufficiency,m etc.) leads to underestimation of severity of the patient’s condition and to failer of algorithm of polymodal intensive therapy. Development of severe complications(sepsis, septic shock, sharp respirator distress-syndrome) demands expansion for epidemic of specialized medicalstructures on rendering timely intensive therapy and resuscitation.