Clinical experience with ursodeoxycholic acid (Urdoxa) in complex therapy of chronic viral hepatitis
https://doi.org/10.22625/2072-6732-2011-3-3-42-45
Abstract
Patients with chronic virus hepatitis (32 patients, 13 with chronic hepatitis B and 19 with chronic hepatitis C) ages from 20 to 72 with elevated levels of bilirubin and active alanine aminotransferase, aspartate aminotransferase, gamma- glutamyl transpeptidase, received ursodeoxycholic acid (Urdoxa) over the course of 12 weeks. During therapy alanine aminotransferase, aspartate aminotransferase, bilirubin and gamma-glutamyl transpeptidase levels decreased. Urdoxa demonstrated good tolerance, efficacy and no visible side effects. Thus, Urdoxa could be used in treatment of chronic viral hepatitis with cytolytic and cholestatic syndromes.
About the Authors
E. V. Esaulenko
Saint-Petersburg State Pediatric Medical Academy, Saint-Petersburg
Russian Federation
Russian Federation
O. E. Nikitina
Research Institute of Influenza, Saint-Petersburg
Russian Federation
Russian Federation
N. V. Dunaeva
Research Institute of Influenza, Saint-Petersburg
Russian Federation
Russian Federation
A. N. Uskov
Research Institute of Children Infection Diseases FMBA of Russia, Saint-Petersburg
Russian Federation
Russian Federation
T. L. Mogilevets
Yaroslav-the-Wise Novgorod State University, Velikiy Novgorod
Russian Federation
Russian Federation
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Review
For citations:
Esaulenko E.V., Nikitina O.E., Dunaeva N.V., Uskov A.N., Mogilevets T.L. Clinical experience with ursodeoxycholic acid (Urdoxa) in complex therapy of chronic viral hepatitis. Journal Infectology. 2011;3(3):42-45. (In Russ.) https://doi.org/10.22625/2072-6732-2011-3-3-42-45
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