Clinical and laboratory diagnosis of dengue fever in travelers
https://doi.org/10.22625/2072-6732-2015-7-1-65-69
Abstract
The paper presents the analysis of clinical and laboratory symptoms in 35 adult patients with denger fever, Novosibirsk residents, which travelled in endemic countries, mostly Tailand. The classic form of the disease was determined in all cases. The moderate form was in 71,5% patients, the severe form was in the rest ones. The diagnosis of dengue was verified by detection of specific immunoglobulin M and in some cases immunoglobulin G and also virus dengue NS1 antigen by immunochromatography. The dominant clinical symptoms in observed patients were fever for 3–8 days (100%), mostly high one (71,4%), asthenia (97,1%), anorexia (100%), myalgia or/and arthralgia (77,1%), exantema (60%), hepatomegaly (62,8%). The gematologic indicators were represented with thrombocytopenia in 91,4% patients (from 167 to 20×109/l) и leucopenia in 85,7% patients (from 3,9 to 1,1×109/l). The cytolitic syndrom was revealed in 80% patients with predominance of aspartate aminotransferase activity in early period of the disease.
About the Authors
N. I. Khokhlova
Novosibirsk State Medical University, Novosibirsk, Russia
Russian Federation
Russian Federation
E. I. Krasnova
Novosibirsk State Medical University, Novosibirsk, Russia
Russian Federation
Russian Federation
L. L. Pozdnyakova
City Infectious Clinical Hospital No 1, Novosibirsk, Russia
Russian Federation
Russian Federation
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Review
For citations:
Khokhlova N.I., Krasnova E.I., Pozdnyakova L.L. Clinical and laboratory diagnosis of dengue fever in travelers. Journal Infectology. 2015;7(1):65-69. (In Russ.) https://doi.org/10.22625/2072-6732-2015-7-1-65-69
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