Experience of application of antitubercular and anti-retrovirus therapy at patients with tuberculosis with HIV infection
https://doi.org/10.22625/2072-6732-2014-6-3-51-55
Abstract
In the territory of the Omsk region HIV infection and tuberculosis at patients come to light at the same time (61,0%) more often. Combination of these two infectious diseases men (81,5%), aged from 30 till 39 years (45,0%) at which the parenteral way of infection (87,3%) HIV infection prevailed are subject to a thicket. Tuberculosis, in this group of patients came to light at early stages of HIV infection (74,5%) that affected frequent percent of infiltrative tuberculosis of lungs (45,5%). Among patients tuberculosis in a combination HIV infection the low motivation to treatment met, however at an assessment of efficiency of treatment of tuberculosis data similar to those at patients with the isolated tuberculosis were obtained. From treatment we explain good effect with a combination of antitubercular therapy with antiretrovirus.
About the Authors
A. V. MordykRussian Federation
L. V. Puzyreva
Russian Federation
S. V. Sitnikova
Russian Federation
References
1. Mishin V.Yu. Tuberkulez at HIV-infected / V.Yu. Mishin //Consilium Medicum. – 2008. – T.10, №. 10. – P. 23-27.
2. Frolova O.P. Tuberkulez at patients with HIV infection: epidemiological situation main directions of the antitubercular help to sick HIV infection / O.P. Frolova. – M.: Center of the antitubercular help to the patient with Russian Federation HIV infection, 2010. – 20 p.
3. Nechayeva O.B. Epidemicheskaya a situation on tuberculosis and HIV infection in Russian Federation / O.B. Nechayeva, N.V. Eysmont // Social aspects of health of the population [The electronic scientific magazine]. – 2012. №. 2 (24). URL: http://vestnik.mednet.ru/content/view/399/30/lang, ru/. – [Date of the address 12.03.2014].
4. Tuberculosis in combination with HIV infection in the territory of the Omsk region from 2008 on 2012 / A.V. Mordyk [i dr.] // HIV infection and immunosupressiya. – 2014. – № 2, volume 6. – P. 106-110.
5. Epidemiological situation on HIV infection in the Omsk region with 1996 on 2013 years / A.V. Mordyk [i dr.] // Medical almanac. – 2014. – № 2 (37). – P. 62-64.
6. Zagdyn Z.M. Combined pathology: tuberculosis and HIV infection in the northwest of Russia / Z.M. Zagdyn, V.B. Galkin, G.S. Balasanyants // Infektologiya Magazine. – 2013. – №. 3. T.5 – P. 19-27.
7. Kozhushko M.Yu. Clinical features of tuberculosis at HIV-infected / M.Yu. Kozhushko, I.V. Yevstigneyev // Therapia – №. 9 (50). – 2010. – P. 11-17.
8. Buman W.J. Treatment of HIV related tuberculosis in the era of effective antiretroviral therapy / W.J. Buman, B.E. Jones // Am. J. Respir. Crit. Care Med. – 2001. – Vol. 164. – P. 7-12.
9. Outcome of HIV – associated tuberculosis in the era of highly active antiretroviral therapy / K. Dheda [et al.] // J. Infect. Dis. – 2004. – Vol. 190, № 9. – P. 1670-1676.
10. Effects of HIV status and other variables on the outcome of tuberculosis treatment in Spain, Grupo de Trabajo del PMIT – 2 / M.D. Ruiz-Navarro [et al.] // Arch. Bronconeumol. – 2005. – Vol. 41, № 7. – P. 363-370.
11. Challenges of diagnosis and management of tuberculosis and HIV coinfection in resource-limited settings: a case report from Lima, Peru / C. Rojas [et al.] // JIAPAC. – 2008. – Vol. 5. – P. 232-237.
12. Treatment outcome of tuberculosis patients diagnosed with human immunodeficiency virus infection in Iran / P. Tabarsi [et al.] // 17th European Congress of Clinical Microbiology and Infections Diseases. – Munich. – Germany, 2007. – Abstract № 1733. – P. 125-127.
13. Kliniko-laboratornaya the characteristic of cases of sharp HIV infection with defeat central nervous system / V.B. Musatov [et al.] // Infektologiya Magazine. – 2012. – №. 2. T. 4. – P. 40-45.
14. Tuberculosis treatment at sick HIV infection /V.N. Zimin [et al.] // Tuberculosis and diseases of lungs. –2011. – № 11. – P. 3-9.
15. Panteleev A.M. Complex treatment of tuberculosis of lungs at HIV infection with application of regionarny limfotropny therapy: abstract of the candidate of medical sciences / A.M. Panteleev; St. Petersburg state medical academy of I.I. Mechnikov. – St. Pb. – 2005. – 24 p.
16. The analysis of application of individual modes of treatment of tuberculosis at sick HIV infection / A.V. Mishina [i dr.] // Pulmonology. – 2013. – №. 4. – P. 61-67.
17. Panteleev A.M. VAART’S application for HIV – infected, patients with tuberculosis [An electronic resource] / A.M. Panteleev, A.G.Rahmanova. – Access mode: http://tb-hiv.ru/ publikation/collaborative_study3/. – [Date of the address 24.07.2014].
18. Chernov M.T. Criteria of evaluation of the work of office of diagnostics and treatment of tuberculosis, combined with HIV infection / M.T. Chernov, S.V. Smerdin, O.P. Frolova // Tuberculosis and diseases of lungs. – 2011. – №. 5. – P. 223-224.
19. About improvement of antitubercular actions in the Russian Federation: order of 21.03.2003. No. 109 / Ministry of Health of the Russian Federation // ConsultantPlus: справ. – legal system. – Access mode: http://www.consultant. ru/
Review
For citations:
Mordyk A.V., Puzyreva L.V., Sitnikova S.V. Experience of application of antitubercular and anti-retrovirus therapy at patients with tuberculosis with HIV infection. Journal Infectology. 2014;6(3):51-55. (In Russ.) https://doi.org/10.22625/2072-6732-2014-6-3-51-55