jofinЖурнал инфектологииJournal Infectology2072-6732IPO “АIDSSPbR"10.22625/2072-6732-2014-6-3-51-55jofin-340Research ArticleОригинальные исследованияOriginal ResearchОПЫТ ПРИМЕНЕНИЯ ПРОТИВОТУБЕРКУЛЕЗНОЙ И АНТИРЕТРОВИРУСНОЙ ТЕРАПИИ У БОЛЬНЫХ ТУБЕРКУЛЕЗОМ С ВИЧ -ИНФЕКЦИЕЙExperience of application of antitubercular and anti-retrovirus therapy at patients with tuberculosis with HIV infectionМордыкА. В.MordykA. V.

заведующая кафедрой фтизиатрии и фтизиохирургии Омской государственной медицинской академии, д.м.н.; тел.: 8(3812)40-45-15

amordik@mail.ruПузыреваЛ. В.PuzyrevaL. V.

ассистент кафедры фтизиатрии и фтизиохирургии Омской государственной медицинской академии, заведующая отделением легочного туберкулеза № 2 Клинического противотуберкулезного диспансера № 4, к.м.н.; тел.: 8(3812)40-45-15

puzirevalv@mail.ruСитниковаС. В.SitnikovaS. V.

аспирант кафедры фтизиатрии и фтизиохирургии Омской государственной медицинской академии, заместитель главного врача по лечебной работе Клинического противотуберкулезного диспансера № 4; тел.: 8(3812)33-03-46

sveta_kptd@mail.ruОмская государственная медицинская академия, Омск, РоссияРоссияOmsk State Medical Academy, Omsk, RussiaRussian FederationОмская государственная медицинская академия, Омск, Россия Клинический противотуберкулезный диспансер № 4, Омск, РоссияРоссияOmsk State Medical Academy, Omsk, Russia Аntitubercular Clinic № 4, Omsk, RussiaRussian Federation201420102014635155Copyright © Мордык А.В., Пузырева Л.В., Ситникова С.В., 20142014Мордык А.В., Пузырева Л.В., Ситникова С.В.Mordyk A.V., Puzyreva L.V., Sitnikova S.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.niidi.ru/jofin/article/view/340

На территории Омской области ВИЧ-инфекция и туберкулез у больных чаще выявляются одновременно (61,0%). Сочетанием этих двух инфекционных заболеваний чаще подвержены мужчины (81,5%) в возрасте от 30 до 39 лет (45,0%), с преобладанием парентерального пути заражения ВИЧ (87,3%). Туберкулез в данной группе больных выявлялся на ранних стадиях ВИЧ-инфекции (74,5%), что повлияло на высокий процент инфильтративного туберкулеза легких (45,5%) в структуре клинических форм. Среди больных туберкулезом в сочетании с ВИЧ-инфекцией встречалась низкая мотивация к лечению, однако при оценке эффективности лечения туберкулеза были получены данные, сопоставимые с таковыми у больных с изолированным туберкулезом.

In the territory of the Omsk region HIV infection and tuberculosis at patients come to light at the same time (61,0%) more often. Combination of these two infectious diseases men (81,5%), aged from 30 till 39 years (45,0%) at which the parenteral way of infection (87,3%) HIV infection prevailed are subject to a thicket. Tuberculosis, in this group of patients came to light at early stages of HIV infection (74,5%) that affected frequent percent of infiltrative tuberculosis of lungs (45,5%). Among patients tuberculosis in a combination HIV infection the low motivation to treatment met, however at an assessment of efficiency of treatment of tuberculosis data similar to those at patients with the isolated tuberculosis were obtained. From treatment we explain good effect with a combination of antitubercular therapy with antiretrovirus.

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The authors declare that there are no conflicts of interest present.