Pleurisy in tuberculosis and HIV-infected patients
https://doi.org/10.22625/2072-6732-2014-6-1-24-28
Abstract
A clinical and epidemiological study for 14 years was conducted. Among TB patients, the percentage of persons with mixed infection (TB+HIV infection) increased during the observation period from 10 up to 64%. About one third of them had a pleura reaction with an accumulation of fluid between pleura’s petals. Pleuritis in patients with mixed infection were characterized by special features: pleurisy complicated another form of tuberculosis more often, in one-third of patients (29,8%) pleural liquid had hemorrhagic type, Mycobacterium tuberculosis in the pleural fluid was detected six times more often. The level of activity of adenosine deaminase and neopterin in the exudate of patients with tuberculosis and HIV infection remained significantly higher than in the control group of persons. These data can be useful in the diagnostics of specific diseases in HIV-infected patients.
About the Authors
A. K. Ivanov
Science Research Institute of Phthysiopulmonology, Saint-Petersburg, Russia
Russian Federation
Russian Federation
G. V. Maksimov
City Antitubercular Dispenser, Saint-Petersburg, Russia
Russian Federation
Russian Federation
S. L. Mukomolov
Saint-Petersburg Science Research Institute of Epidemiology and Microbiology named after Pasteur, Saint-Petersburg, Russia
Russian Federation
Russian Federation
D. S. Esmеrdlayeva
Science Research Institute of Phthysiopulmonology, Saint-Petersburg, Russia
Russian Federation
Russian Federation
M. Yu. Popov
City Antitubercular Dispenser, Saint-Petersburg, Russia
Russian Federation
Russian Federation
T. L. Petrova
Science Research Institute of Phthysiopulmonology, Saint-Petersburg, Russia
Russian Federation
Russian Federation
E. A. Malashenkov
Clinical Hospital of Infectious Diseases named after S.P. Botkin, Saint-Petersburg, Russia
Russian Federation
Russian Federation
References
1. Zimina VN, Batyrov FA, Kravchenko AV, et al. Tuberkulez i bolezni legkikh. 2013; 9: 27–32.
2. Ivanov AK, Sakra AA, Nechayev VV, et al. Tuberkulez i virusnyye gepatity: staryye i novyye problemy [Tuberculosis and viral hepatitis: old and new challenges]. In: Proceedings of the II Congress of National Association of phthisiologists. St.Petersburg; 2013. p. 182–3.
3. Kornilova ZKh, Lukonina IV, Alekseyeva LP. Tuberkulez i bolezni legkikh. 2010; 3: 3–9.
4. Okhtyarkina VV, Novoselov PN, Bolotov AA, et al. Tuberkulez i bolezni legkikh. 2011; 9: 23-6.
5. Panteleyev AM. Patogenez, klinika, diagnostika i lecheniye tuberkuleza u bolnykh VICh-infektsiyey [Pathogenesis, clinical features, diagnosis and treatment of tuberculosis in HIV-infected patients] [dissertation]. StPetersburg (Russia); 2012. 45р. Russian.
6. Alekseyeva LP. Osobennosti vyyavleniya, klinicheskogo techeniya i lecheniya bolnykh tuberkulezom i VICh-infektsiyey [Features detection, clinical course and treatment of tuberculosis and HIV infection] [master´s thesis]. Moscow (Russia); 2008. 21p. Russian.
7. Batyrov FA. Lechebno-diagnosticheskaya pomoshch bolnym tuberkulezom s VICh-infektsiyey v usloviyakh mnogoprofilnoy spetsializirovannoy bolnitsy [Treatment and diagnostic services to patients with tuberculosis and HIV infection in a multidisciplinary environment Specialized Hospital] [dissertation]. Moscow (Russia); 2004. 27p. Russian.
8. Popov MYu. Osobennosti diagnostiki i lecheniya empiyemy plevry tuberkuleznoy etiologii v usloviyakh ftiziatricheskogo statsionara [Diagnosis and treatment of pleural empyema tubercular etiology in terms of TB hospital] [master´s thesis]. StPetersburg (Russia); 2003. 25р. Russian.
9. Goto M, Noguchi Y, Koyama H, et al. Diagnostic value of adenosine desaminase in tuberculosis pleural effusion: a meta-analysis. Ann. Clin. Biochem. 2003; 40, (4). р. 374–81.
10. Aoki G, Katoh O, Nakamshi Y, et al. A comparison study of INF-γ, ADA and Ca125 as diagnostic parameters in tuberculosis pleuritis Respir. Med. 1994; 88(1). р. 139–43.
11. Tian R, Gao Z. Clinical investigation of the diagnostic value of interferon-gamma, interleukin-12 and adenosine isoenzyme in tuberculosis pleurisy. Zhonghua Jie He He Hu Xi Za Zhi. 2004; 27(7). р. 435–438.
12. Titarenko OT, Esmedlyayeva DS, Dyakova ME, et al. Problemy tuberkuleza. 2008; 12: 27–30.
13. Titarenko OT, Esmedlyayeva DS, Perova TL, et al. Klinicheskaya laboratornaya diagnostika. 2010; 1: 46–9.
14. Esmedlyayeva DS, Dyakova ME, Perova TL, et al. Klinicheskaya znachimost opredeleniya kontsentratsii neopterina v krovi bolnykh razlichnymi formami tuberkuleza legkikh [Clinical significance of determination of neopterin concentrations in the blood of patients with various forms of pulmonary tuberculosis] In: Innovatsionnyye tekhnologii v organizatsii ftiziatricheskoy i pulmonologicheskoy pomoshchi naseleniyu [Innovative technologies in the organization and pulmonology care to the population]. StPetersburg (Russia); 2012. р 126–8. Russian.
Review
For citations:
Ivanov A.K., Maksimov G.V., Mukomolov S.L., Esmеrdlayeva D.S., Popov M.Yu., Petrova T.L., Malashenkov E.A. Pleurisy in tuberculosis and HIV-infected patients. Journal Infectology. 2014;6(1):24-28. (In Russ.) https://doi.org/10.22625/2072-6732-2014-6-1-24-28
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