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Central motor pathways involvement in patients with aseptic meningitis

https://doi.org/10.22625/2072-6732-2014-6-1-19-23

Abstract

Aim of our study was to investigate central motor pathways involvement in children in early recovery period after the aseptic meningitis.


Materials and methods: 65 patients (40 children with average age 12 years with aseptic meningitis and 25 age matched controls) were enrolled. TMS (single-pulse protocol) with MEP shape, latency and amplitude and CMCT averaged and analyzed.


Results: In aseptic meningitis group in 69–73% of the patients diffuse TMS parameters changes were seen (MEPs amplitudes lowering). These changes may be interpreted as motoneurons diffuse functional activity lowering, but also as a signs of neurodegenerative process of a certain degree. Axonal lesions (MEPs latency lengthening) was registered in 12–15% of the patients of aseptic meningitis group.


Conclusion. When aseptic meningitis in most cases, signs of diffuse lesion of motoneurons

About the Authors

V. B. Voitenkov
Science Research Institute of Children’s Infections of FMBA of Russia, Saint-Petersburg, Russiaности
Russian Federation


N. V. Skripchenko
Science Research Institute of Children’s Infections of FMBA of Russia, Saint-Petersburg, Russiaности
Russian Federation


N. V. Matyunina
Science Research Institute of Children’s Infections of FMBA of Russia, Saint-Petersburg, Russiaности
Russian Federation


A. V. Klimkin
Science Research Institute of Children’s Infections of FMBA of Russia, Saint-Petersburg, Russiaности
Russian Federation


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Review

For citations:


Voitenkov V.B., Skripchenko N.V., Matyunina N.V., Klimkin A.V. Central motor pathways involvement in patients with aseptic meningitis. Journal Infectology. 2014;6(1):19-23. (In Russ.) https://doi.org/10.22625/2072-6732-2014-6-1-19-23

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ISSN 2072-6732 (Print)