Clinical observations of giant cell hepatitis in children
https://doi.org/10.22625/2072-6732-2019-11-4-153-160
Abstract
Giant cell hepatitis is characterized, by inflammation and large multinucleated. hepatocytes in hepatic parenchyma It is an unusual hepatocytes response to various noxious stimuli, characterized, by presence of multinucleated cells in liver with generally dismal clinical outcome. Giant cell hepatitis is commonly reported, in neonatal and. infantile liver diseases but rarely in adults (postinfantile giant cell hepatitis). Giant cell hepatitis is associated, with many diseases, including drugs toxicity, viral and. autoimmune liver diseases, with autoimmune hepatitis being the most prevalent. We report some clinical cases of giant cell hepatitis with review of literature regarding various etiological agents and their respective prognostic outcome.
About the Authors
E. N. Sergienkci
Belarusian state medical university
Belarus
Minsk
Competing Interests: not
Belarus
Minsk
Competing Interests: not
O. N. Romanova
Belarusian state medical university
Belarus
Minsk
Competing Interests: not
Belarus
Minsk
Competing Interests: not
A. A. Klyuchareva
Belarusian medical academy of postgraduate education
Belarus
Minsk
Competing Interests: not
Belarus
Minsk
Competing Interests: not
N. V. Klimovich
Belarusian medical academy of postgraduate education
Belarus
Minsk
Competing Interests: not
Belarus
Minsk
Competing Interests: not
S. K. Kletskiy
Minsk city clinical pathoanatomical bureau
Belarus
Minsk
Competing Interests: not
Belarus
Minsk
Competing Interests: not
I. V. Sakharov
Minsk city clinical pathoanatomical bureau
Belarus
Minsk
Competing Interests: not
Belarus
Minsk
Competing Interests: not
T. I. Lisitskaya
City children's infectious clinical hospital
Belarus
Minsk
Competing Interests: not
Belarus
Minsk
Competing Interests: not
A. M. Kashkan
City children's infectious clinical hospital
Belarus
Minsk
Competing Interests: not
Belarus
Minsk
Competing Interests: not
M. D. Ocheretny
City children's infectious clinical hospital
Belarus
Minsk
Competing Interests: not
Belarus
Minsk
Competing Interests: not
E. A. Buldyk
City children's infectious clinical hospital
Belarus
Minsk
Competing Interests: not
Belarus
Minsk
Competing Interests: not
V. P. Grinchak
City children's infectious clinical hospital
Belarus
Minsk
Competing Interests: not
Belarus
Minsk
Competing Interests: not
Yu. V. Strizhak
City children's infectious clinical hospital
Belarus
Minsk
Competing Interests: not
Belarus
Minsk
Competing Interests: not
References
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Review
For citations:
Sergienkci E.N., Romanova O.N., Klyuchareva A.A., Klimovich N.V., Kletskiy S.K., Sakharov I.V., Lisitskaya T.I., Kashkan A.M., Ocheretny M.D., Buldyk E.A., Grinchak V.P., Strizhak Yu.V. Clinical observations of giant cell hepatitis in children. Journal Infectology. 2019;11(4):153-160. (In Russ.) https://doi.org/10.22625/2072-6732-2019-11-4-153-160
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