The cryptosporidiosis in HIV-infected patients – diagnostic, clinical and laboratory manifestation
https://doi.org/10.22625/2072-6732-2012-4-2-26-32
Abstract
The representatives of genus Cryptosporidium were found in 17 of 99 (17, 2%) HIV patients in Clinical Infectious Diseases Hospital named after S.P. Botkin. The restriction fragment length polymorphism (RFLP) assay identified two types of these agents Сriprtosporidium parvum in 11 (64,7%) and C. hominis in 6 (35,3%) patients. The level of CD4+ lymphocyte in the patients having cryptosporidiosis was significantly lower than in patients without cryptosporidiosis. In patients with cryptosporidiosis prolonged diarrhea were found at significantly higher rate. Also the patients with cryptosporidiosis demonstrated malnutrition and weight loss, but not at significantly higher rates. The present study is one of the first describe of cryptosporidiosis in Russia.
About the Authors
O. I. Sokolova
Saint-Petersburg State University, Saint-Petersburg
City Infectious Disease Hospital named by S.P. Botkin, Saint-Petersburg
Russian Federation
Russian Federation
A. V. Demyanov
Institute of Pure Biopreparations, Saint-Petersburg
Russian Federation
Russian Federation
V. A. Dedov
Institute of Pure Biopreparations, Saint-Petersburg
Russian Federation
Russian Federation
Yu. Ya. Sokolova
Institute of Cytology Russian Academy of Sciences, Saint-Petersburg
Louisiana State University School of Veterinary Medicine, Baton Rouge, USA
Russian Federation
Russian Federation
A. A. Yakovlev
Saint-Petersburg State University, Saint-Petersburg
City Infectious Disease Hospital named by S.P. Botkin, Saint-Petersburg
Russian Federation
Russian Federation
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Review
For citations:
Sokolova O.I., Demyanov A.V., Dedov V.A., Sokolova Yu.Ya., Yakovlev A.A. The cryptosporidiosis in HIV-infected patients – diagnostic, clinical and laboratory manifestation. Journal Infectology. 2012;4(2):26-32. (In Russ.) https://doi.org/10.22625/2072-6732-2012-4-2-26-32
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