A retrospective clinical and epidemiological analysis of cases of hepatitis E in St. Petersburg
https://doi.org/10.22625/2072-6732-2012-4-1-65-67
Abstract
Hepatitis E – zoonotic disease that has received a nosological independence twenty years ago, when Russian scientist, Professor M.S. Balayan, identified the pathogen (hepatitis E). It was believed that the disease can manifest itself only in the acute form, and occur only in regions with subtropical and tropical climate conditions. The development and introduction of practicing of modern scientific research methods for detecting antibodies to activator change, to view the global prevalence of infection and present doubts on inabilities of transformation into a chronic f a retrospective analysis of hospital cases of acute jaundice hepatitis E in Saint-Petersburg.
Etiologic accessory to hepatitis E implemented by discovery in serum of patients a specific marker of infection hepatitis E – an anti-HEV.
In the analysis of archive documentation for 2000–2011 from the patients which were hospitalized in the Clinical Infectious Diseases Hospital by S.P. Botkin only 11patients were diagnosed with «acute hepatitis E». Which indicates the presence of patients with acute hepatitis E infection among hospitalized in hospitals of the city of St. Petersburg are not endemic for this disease. The presence of cases of disease of the indigenous inhabitants of the city during the past years, which isn’t going beyond its limits, indicates the existence of «autochthonous» hepatitis E.
About the Authors
H. D. Peradze
Ministry of Healthcareand Social Development of the Russian Federation «Saint-Petersburg State Pediatric Medical Academy», Saint Petersburg
Russian Federation
Russian Federation
E. V. Esaulenko
Ministry of Healthcareand Social Development of the Russian Federation «Saint-Petersburg State Pediatric Medical Academy», Saint Petersburg
Russian Federation
Russian Federation
E. Y. Malinnikova
Ministry of Healthcare and Social Development of the Russian Federation «Institute of Poliomyelitis and Viral Encephalitis after M.P. Chumakov», Moscow region
Russian Federation
Russian Federation
M. I. Mihaylov
Ministry of Healthcare and Social Development of the Russian Federation «Institute of Poliomyelitis and Viral Encephalitis after M.P. Chumakov», Moscow region
Russian Federation
Russian Federation
References
1. Фаворов, М.О. Распространенность антител к вирусу гепатита Е среди грызунов в Соединенных Штатах /М.О. Федоров [и др.] // Журнал инфекционных болезней. – 2000. – № 181 (2). – С. 449–455.
2. Михайлов, М.И. Групповая заболеваемость гепатитом Е в г. Коврове Владимирской области / М.И. Михайлов [и др.] // Труды Института полиомиелита и вирусных энцефалитов им. М.П. Чумакова РАМН. – Т. 26. Материалы науч.-практ. конф. «Актуальные проблемы медицинской вирусологии». – С. 239–245.
3. Цыганова, Е.В. Острый гепатит неуточненной этиологии РЖГГК / Е.В. Цыганова [и др.]. – 2011. – Т. 21, № 1. –С. 32–39.
4. Pursell, R.H. Hepatitis E: an emerging awareness of an old disease / R.H. Pursell, S.U. Emerson // J. Hepatol. – 2008. – № 48. – Р. 494–503.
5. Borgen, K. Non-travel related Hepatitis E virus genotype 3 infections in the Netherlands; a case series 2004–2006 /K. Borgen [et al.] // BMC infect. Dis. – 2008. – № 8. – Р. 61.
6. Dalton, H.R. Autochthonous hepatitis E in Southwest England: a comparison with hepatitis A / H.R. Dalton [et al.] // Eur. J. Clin. Microbiol. Infect. Dis. – 2008. – № 27. – Р. 579–585.
7. Gerolami, R. Chronic hepatitis E with cirrhosis in a kidney-transplant recipient / R. Gerolami, V. Moal // N. Engl. J. Med. – 2008. – № 358. – Р. 859–860.
Review
For citations:
Peradze H.D., Esaulenko E.V., Malinnikova E.Y., Mihaylov M.I. A retrospective clinical and epidemiological analysis of cases of hepatitis E in St. Petersburg. Journal Infectology. 2012;4(1):65-67. (In Russ.) https://doi.org/10.22625/2072-6732-2012-4-1-65-67
Views:
731
.png)
.png)
Email this article 