EPIDEMIOLOGICAL FEATURES AND EVOLUTION OF CLINICAL PRESENTATION OF TYPHOID FEVER IN SAINT-PETERSBURG
https://doi.org/10.22625/2072-6732-2019-11-1-25-32
Abstract
Purpose: To study an epidemiological features and evolution of clinical presentation of typhoid fever in modern megapolis
Materials and methods: A study of 115 patient’s medical records was performed. All patients were hospitalized in Clinical Infectious Diseases Hospital named after S.P. Botkin, Saint-Petersburg, Russia during 2005–2017 with confirmed diag№sis of typhoid fever. We have conducted a comparison of epidemiological and clinical features between 59 patients hospitalized in 2005–2009 and 56 hospitalized in 2010–2017.
Results: There was increase proportion of Central Asia’ countries citizens among study group during recent years. Social status of affected patients had also changed recently due to decrease fraction of homeless people along with decreased number of patients with accompanied infectious diseases. Atypical clinical presentation had become more common №wadays with most of a patients presented with moderate severity form of disease.
Conclusion: Clinical presentation and epidemiology of typhoid fever are prone to changes over time. New data on epidemiology and predominance of atypical form of disease need to be considered to ensure prompt diag№sis of a disease.
About the Authors
K. E. Novak
Saint-Petersburg State Pediatric Medical University.
Russian Federation
Russian Federation
A. G. Dyachkov
Clinical Infectious Diseases Hospital named after S.P. Botkin.
Russian Federation
Russian Federation
E. V. Esaulenko
Saint-Petersburg State Pediatric Medical University.
Russian Federation
Russian Federation
References
1. Kaftyreva L.A., Egorova S.A., Kozyreva V.K., Makarova M.A., Vojtenkova E.V., Matveeva Z.N., Zabrovskaya A.V., Suzhaeva L.V. Feature softyphoid fever in Russian Federation // Dal’nevostochnyj Zurna lInfekcionnoj Patologii. –2012. – № 21. – S. 101–108.
2. Suhoruk A.A., Gordievkaya E.G., Esaulenko E.V. Contemporary clinical presentation of typhoid fever. Zurnal infektologii. 2015. T. 7. №S3. S. 82-83.3. Yakovlev A.A., Kotlyarova S.I., Cherenkova G.YU., Pershin S.S., Kaftyreva L.A., Musatov V.B. The clinical and laboratory picture of typhoid in a megapolis. Epidemiologiya I infekcionnye bolezni. 2010. № 2. S. 27-303.
3. WHO. Typhoid fever. Questions and answers. January 2018 g. [Online resource]. Avaliable at: http://www.who.int/features/qa/typhoid-fever/ru/ (Accessed: 21.11.2018).
4. Belyaeva N.M., Pogorel’skaya L.V., Shestakova I.V., Kaftyreva L.A., Iva№va L.P., Nikiforov V.V., Shahmarda№v M.Z., Sokolova L. V. Clinical guidelines (treatment protocol) for adults with typhoid fever (infectious disease caused by Salmonella typhi) [Online resource]. Avaliable at: http://iia-rf.ru/upload/iblock/bd3/bd39c89f786895b48e9d46eb866ad051.pdf (Accessed: 21.11.2018).
5. O sostoyanii sanitarno-ehpidemiologicheskogo blagopoluchiya naseleniya v Rossijskoj Federacii v 2013 godu: Gosudarstvennyj doklad Federal’noj sluzhby po nadzoru v sfere zashchity prav potrebitelej I blagopoluchiya cheloveka. –2014. –192 s.
6. Kaftyreva L.A., Matveeva Z.N., Egorova S.A. Epidemiological patterns of typhoid fever Infekciya I immunitet. 2017. № S. S. 29.
7. Infekcionnaya zabolevaemost’ v Rossijskoj Federacii za yanvar’-dekabr’ 2017 g. [Online resource] Avaliable at: http://www.rospotrebnadzor.ru/activities/statisticalmaterials/statictic_details.php?ELEMENT_ID=10049 (Accessed: 21.10.2018).
8. Kovalenko A. N., Iva№v A. M., Odinaev N. S., Rahma№v
9. M. I., Murachev A. A. Thypoid fever: experience from last decade // Zurnal infektologii. –2009. – T. 1, № 2/3. – S. 69–72.
10. Rahmanov EH.R., Kamardinov H.K., Mati№v SH.K., Melikov Z.M., Gulyamova N.M. Antibiotic resistance profile of Sal. Typhi and its influence on treatment of typhoid fever // Nauchno-medicinskij zhurnal «Vestnik Avicenny». – 2012. – № 2. – S. 134-136.
11. Gatifloxacin for treating enteric fever Submission to the 18th Expert Committee on the
12. Selection and Use of Essential Medicines. WHO 21-25.03.2011.Available at:http://www.who.int/selection_medicines/committees/expert/18/en/(21.11.2018).
13. Olarte, J. Salmonella typhi resistant tochloramphenicol, ampicillin, and other antimicrobial agents: strains isolated during anextensive typhoid fever epidemic in Mexico / J. Olarte, E. Galindo // Antimicrob. Agents Chemother. – 1973. – Vol. 4. – P. 597–601.
14. Chau TT. Antimicrobial drug resistance of Salmonella enterica serovar typhi in asia and molecular mechanism of reduced susceptibility to the fluoroqui № lones / T.T. Chau [et al.] // Antimicrob. Agents Chemother. – 2007. – Vol. 51, N 12. – P. 4315–4323.
15. Connerton, P. Epidemic typhoid in Vietnam: molecular typing of multiple-antibiotic-resistant Salmonella enterica serotype typhi from four outbreaks / P. Connerton [et al.] // J. Clin. Microbiol. – 2000. – Vol. 38, N2. – P. 895–897.
16. Kariuki, S. Characterization of multidrug-resistant typhoid outbreaks inKenya / S. Kariuki [et al.] // J. Clin. Microbiol. – 2004. – Vol. 42, N 4. – P. 1477–1482.
17. Kumar, Y. High level of resistance to nalidixic acid in Salmonella enteric serovar typhi in Central India / Y. Kumar, A. Sharma, KR. Mani Kumar // J. Infect. Dev. Ctries. – 2009. – Vol. 6, N 3. – P. 467– 469.
18. Kumar, R. Multidrug-resistant typhoid fever / R. Kumar, N.S. Gupta // Indian J. Pediatr. – 2007. -Vol. 74. – P. 39–42.
19. Lewis, M.D. Typhoid fever: a massive, single-point source, multidrug-resistant outbreak in Nepal / M.D. Lewis [et al.] // Clin. Infect. Dis. – 2005. – Vol. 40. – P. 554–561.
20. Mandal, S. Synergism of ciprofloxacin and trimethoprim against Salmonella enterica serovar typhi isolates showing reduced susceptibility to ciprofloxacin / S. Mandal, M.D. Mandal, N.K. Pal // Chemotherapy 2004. – Vol. 50. – P. 152–154.
Review
For citations:
Novak K.E., Dyachkov A.G., Esaulenko E.V. EPIDEMIOLOGICAL FEATURES AND EVOLUTION OF CLINICAL PRESENTATION OF TYPHOID FEVER IN SAINT-PETERSBURG. Journal Infectology. 2019;11(1):25-32. (In Russ.) https://doi.org/10.22625/2072-6732-2019-11-1-25-32
Views:
1095
.png)
.png)
Email this article 