Laboratory diagnostics acute respiratory virus infections under evolutionary variability influenza viruses

V. F. Suhovetskaya; E. A. Dondurey; V. P. Drinevsky; A. A. Sominina; V. G. Majorova; M. M. Pisareva; T. M. Gudkova; I. V. Amosova; V. Z. Krivitskaya; A. K. Golovanova

doi:10.22625/2072-6732-2012-4-1-36-41

Laboratory diagnostics acute respiratory virus infections under evolutionary variability influenza viruses

V. F. Suhovetskaya, E. A. Dondurey, V. P. Drinevsky, A. A. Sominina, V. G. Majorova, M. M. Pisareva, T. M. Gudkova, I. V. Amosova, V. Z. Krivitskaya, A. K. Golovanova

https://doi.org/10.22625/2072-6732-2012-4-1-36-41

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Abstract

As a result of laboratory investigation 1651 patients at the age from 0 months till 18 years, hospitalized with ARI from 2008 to 2011, in ¾ cases the virus etiology of disease was found. At the same time in 2009-2011 was marked significant prevalence of pandemic influenza virus infection A(Н1N1)v in a kind mono- and mikst-infections (in 18,8 and 10,2 % of cases accordingly), and adenoviruses, espiratory sincitial viruses and parainfluenza were the most frequent concomitants (in 4,8, 3,2 and 2,4 % of cases). In a clinical picture of disease acute nasopharynx lesion (67,8 %) was predominated, complicating by croup in 12,2 % of cases, by acute bronchitis in 12,1 % of cases, and more rare by pneumonia (in 8,2 % of cases). The analysis of results of immunofluorescence test in comparison with the cumulative data of other laboratory methods (polymerase chain reaction, immuneenzyme analysis, virus isolation, serological examination) has shown possibility of discovery with its help the valuable information on etiology ARI, including influenza, at early stages of disease and in short terms.

Keywords

viruses, influenza, parainfluenza, adenoviruses, respiratory syncytial virus, infection, children, laboratory diagnosis

About the Authors

V. F. Suhovetskaya

Research Institute of Influenza of Ministry of Health and Social Development of the Russian Federation, Saint-Petersburg Children’s City Clinical Hospital № 5 by N.F. Filatov, Saint-Petersburg
Russian Federation

E. A. Dondurey

V. P. Drinevsky

A. A. Sominina

V. G. Majorova

M. M. Pisareva

T. M. Gudkova

I. V. Amosova

V. Z. Krivitskaya

A. K. Golovanova

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For citations:

Suhovetskaya V.F., Dondurey E.A., Drinevsky V.P., Sominina A.A., Majorova V.G., Pisareva M.M., Gudkova T.M., Amosova I.V., Krivitskaya V.Z., Golovanova A.K. Laboratory diagnostics acute respiratory virus infections under evolutionary variability influenza viruses. Journal Infectology. 2012;4(1):36-41. (In Russ.) https://doi.org/10.22625/2072-6732-2012-4-1-36-41

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Journal Infectology

Laboratory diagnostics acute respiratory virus infections under evolutionary variability influenza viruses

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Abstract

Keywords

About the Authors

References

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