EPIDEMIOLOGICAL CHARACTERISTIC OF HERPES SIMPLEX VIRUS TYPE 2 INFECTION AT A LARGE CENTER OF RUSSIAN ARCTIC ZONE
https://doi.org/10.22625/2072-6732-2017-9-4-119-125
Abstract
Globally, infection caused by herpes simplex virus type 2 (HSV-2) is one of the most prevalent sexually transmitted infections and the most frequent cause of the genital ulcer diseases. The information about HSV-2 epidemiology in Russia is insufficient. Aim of the study: to define the prevalence of HSV-2 among general adult population in Northwest Russia (Arkhangelsk).
Material and methods. The study was a part of a large Norwegian-Russian project and has a population-based cross-sectional design. The agency on social researches recruited residents of Arkhangelsk using a quota sampling method. The ELISA method was used to test the blood samples on Ig G g2; kits of Vector Best (Novosibirsk, Russia) were used.
Results. Altogether, 1243 participants provided the blood samples and fulfilled the questionnaire. Men represented 44% (543 persons) and women – 56 (700 persons), the mean age was 27,6±5,6 and 27,0±5,7 years respectively. Seroprevalence of HSV-2 in the sample was 18,8% (95% CI 16,8– 21,1), seroprevalence among women was in 2 times higher compared with men (24,0%, 95% CI 20,1–27,3 and 12,2%, 95% CI 9,7–15,2 respectively; p<0,001). The percentage of positive results increased with age in both men and women.
Conclusion. According to our data seroprevalence of HSV-2 among young adults in Arkhangelsk was comparable with seroprevalence in some European countries with high figures and with USA. High prevalence of HSV-2 among females in reproductive age shows the potential of this infection in vertical transmission.
About the Authors
T. V. Balaeva
Center of Hygiene and Epidemiology in Arkhangelsk region; Northern State Medical University.
Russian Federation
Arkhangelsk.
Russian Federation
Arkhangelsk.
O. V. Samodova
Northern State Medical University.
Russian Federation
Arkhangelsk.
Russian Federation
Arkhangelsk.
A. L. Sannikov
Northern State Medical University.
Russian Federation
Arkhangelsk.
Russian Federation
Arkhangelsk.
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Review
For citations:
Balaeva T.V., Samodova O.V., Sannikov A.L. EPIDEMIOLOGICAL CHARACTERISTIC OF HERPES SIMPLEX VIRUS TYPE 2 INFECTION AT A LARGE CENTER OF RUSSIAN ARCTIC ZONE. Journal Infectology. 2017;9(4):119-125. (In Russ.) https://doi.org/10.22625/2072-6732-2017-9-4-119-125
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