ПОСЛЕДНИЕ ДОСТИЖЕНИЯ В ЛЕЧЕНИИ ХРОНИЧЕСКОГО ГЕПАТИТА В: С ЧЕГО НАЧИНАТЬ СТАРТОВУЮ ТЕРАПИЮ?


https://doi.org/10.22625/2072-6732-2011-3-4-18-25

Полный текст:


Аннотация

В настоящем обзоре обобщены последние достижения в исследовании эффективности и безопасности противовирусной терапии больных хроническим гепатитом В. Описана современная концепция мониторинга и лечения этих пациентов. Особое внимание уделено прогностическому значению определения уровня НВsАgна этапах контроля лечения. Представлены новые алгоритмы интерферонотерапии и подходы к лечению аналогами нуклеоз(т)идов. Предложено начинать стартовую терапию больных хроническим гепатитом В с пегилированных интерферонов.При отсутствии благоприятных прогностических критериев достижения устойчивого иммунного контроля, а также наличия противопоказаний к интерферонотерапии и развитии нежелательных явлений, требующих ее отмены, пациентов необходимо переводить на лечение нуклеоз(т)идными аналогами.


Об авторе

К. В. Жданов
Военно-медицинская академия имени С.М. Кирова, Санкт-Петербург
Россия

начальник кафедры инфекционных болезней Военно-медицинской академии им. С.М. Кирова, д.м.н., профессор, тел. 8 (812)542-92-14



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Дополнительные файлы

Для цитирования: Жданов К.В. ПОСЛЕДНИЕ ДОСТИЖЕНИЯ В ЛЕЧЕНИИ ХРОНИЧЕСКОГО ГЕПАТИТА В: С ЧЕГО НАЧИНАТЬ СТАРТОВУЮ ТЕРАПИЮ? Журнал инфектологии. 2011;3(4):18-25. https://doi.org/10.22625/2072-6732-2011-3-4-18-25

For citation: Zhdanov K.V. Recent advances in the treatment of chronic hepatitis B: where to start initial therapy? Journal Infectology. 2011;3(4):18-25. (In Russ.) https://doi.org/10.22625/2072-6732-2011-3-4-18-25

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