Tularemia in Arkhangelsk region: clinical and epidemiological aspects
Abstract
Aim: to analyze epidemiological and clinical features of tularemia cases diagnosed between 2010 and 2014 and to identify factors associated with complications.
Methods: We conducted retrospective cohort study including all patients hospitalized with tularemia between 2010 and 2014.
Results: Most of tularemia cases were diagnosed in July (20,8%) and August (57,1%) among adult females (63,6%). The most common forms were bubonic and ulcer-bubonic (89,6%). Buboes were commonly found in the upper femoral and groin regions (92,2%). Diagnostic errors were revealed in 54,1% of cases. The most frequent misdiagnoses were lymphadenitis and fever of unknown origin. Delay in effective antibiotic therapy was associated with an increased rate of complications.
Conclusion: Tularemia has a diversity of clinical presentations. Doctors need to memorize the most common clinical signs of tularemia (fever and lymphadenitis) to make timely diagnosis.
About the Authors
L. V. TitovaRussian Federation
Arkhangelsk
O. V. Samodova
Russian Federation
Arkhangelsk
E. A. Krieger
Russian Federation
Arkhangelsk
T. A. Gordienko
Russian Federation
Arkhangelsk
N. V. Kruglova
Russian Federation
Arkhangelsk
I. V. Shhepina
Russian Federation
Arkhangelsk
Yu. V. Gontova
Russian Federation
Arkhangelsk
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Review
For citations:
Titova L.V., Samodova O.V., Krieger E.A., Gordienko T.A., Kruglova N.V., Shhepina I.V., Gontova Yu.V. Tularemia in Arkhangelsk region: clinical and epidemiological aspects. Journal Infectology. 2016;8(2):78-84. (In Russ.)