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Prevention of post-transfusion hepatitis c transmission through donor blood and its components

https://doi.org/10.22625/2072-6732-2015-7-3-85-90

Abstract

The aim of organizational aspects of preventing the transmission of hepatitis C virus with donor blood and its components.

Materials and methods. An activity of the blood service establishments in Russia for the prevention of HCV infection through transfusion of blood and its components on the basis of the analysis of sectoral statistical surveys was studied.

Results. The frequency of detection of antibodies to hepatitis C virus in blood donors and its components during 2009–2013 decreased by more than 1,5 times. The percentage of donors who have identified markers of hepatitis C virus was significantly different in different regions: from 0,51% to 1,36%. The activity of the blood service implemented method of plasma quarantine resulting annually rejected from 0,32% to 0,23% as a result of the identified markers of HCV. Pathogen inactivated plasma volume increased in 3 times, the platelet concentrate in 3,2 times.

Conclusion. To ensure the safety of donated blood and its components in the blood service effectively the modern technology use for to prevention transmission of the HCV: quarantine of plasma, donor selection and development, inactivation of pathogens. The degree of implementation in practice of nonpaid voluntary blood transfusions significantly increased and is characterized by regional features in recent years .

About the Authors

A. V. Chechetkin
Russian Science Research Institute of Hematology and Transfusiology, Saint-Petersburg, Russia
Russian Federation


V. V. Danilchenko
Russian Science Research Institute of Hematology and Transfusiology, Saint-Petersburg, Russia
Russian Federation


A. D. Kasyanov
Russian Science Research Institute of Hematology and Transfusiology, Saint-Petersburg, Russia
Russian Federation


A. B. Makeev
Russian Science Research Institute of Hematology and Transfusiology, Saint-Petersburg, Russia
Russian Federation


V. E. Soldatenkov
Russian Science Research Institute of Hematology and Transfusiology, Saint-Petersburg, Russia
Russian Federation


V. N. Chebotkevich
Russian Science Research Institute of Hematology and Transfusiology, Saint-Petersburg, Russia
Russian Federation


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Review

For citations:


Chechetkin A.V., Danilchenko V.V., Kasyanov A.D., Makeev A.B., Soldatenkov V.E., Chebotkevich V.N. Prevention of post-transfusion hepatitis c transmission through donor blood and its components. Journal Infectology. 2015;7(3):85-90. (In Russ.) https://doi.org/10.22625/2072-6732-2015-7-3-85-90

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ISSN 2072-6732 (Print)