Nipah Encephalitis – A Dangerous Zooanthroponosis Of Indo-Malaysian Region Of South-Еast Asia
https://doi.org/10.22625/2072-6732-2014-6-3-15-26
Abstract
The review provides information on a new zooanthroponosis – Nipah encephalitis. Characteristics of the pathogen and its ecology and clinic are presented. The purpose of the review is to get Russian specialist acquainted with new dangerous disease unknown in Russia. The research method – analytical. Infection by humans were first described in Malaysia (1999), after in Bangladesh (2004) and India (2006). The causative agent was identified as a new member of paramyxoviruses and then, together with related Hendra virus, separated in a new genus Henipavirus of the family Paramyxoviridae (2000). Reservoir in nature – fruit bats, predominantly carnivorous flying foxes of 8 species of the genus Pteropus, secondary reservoir – domestic pigs. Nipah virus is highly contagious for humans and swine. The last act as amplifying and reservoir host. The disease in
humans is characterized by symptoms and signs of acute encephalitis and pulmonary insufficiency. Rapidly developing coma, lethality – up to 92,0%. Outbreaks with transmission of the virus from person-to-person are known. Specific treatment has not been developed, prevention is nonspecific.
About the Author
E. P. Lukin
48 Central Science Research Institute of Ministry of Defense of Russian Federation, Sergiev Posad (Moscow Region)
Russian Federation
Russian Federation
References
1. Berillo S.A., Demina O.K., Ternovoy V.A., et al. Epidemiologiya i infektsionnyye bolezni. 2012;4:12-15 (in Russian).
2. Panning M, Grywna K, Van Esbroeck M, et al. Chikungunya fever in travelers returning to Europe from Indian Ocean region, 2006. Emerg Infect Dis. 2008;14(3):416-22.
3. Field H, Young P, Job JM, et al. The natural history of Hendra and Nipah viruses. Microbes Infect. 2001;3:307-14.
4. Mackenzie JC, Chua KB, Daniels P, et al. Emerging viral diseases of Southern Asia and the Western Pacific. Emerg Infect Dis. 2001;7(1)(Suppl.):497-504.
5. Breed AC, Meers J, Sendow I, et al. The distribution of Henipavirus in Southeast Asia and Australia: is Wallace’s line a barrier to Nipah virus. PLOS ONE. 2013;8(4):e61316. doi:10.1371/journal.pone.0061316.
6. Kurup A. From bats to pigs to man: the story of the Nipah virus. Infect Dis Clin Pract. 2002;11(2):52-7.
7. Farrar JJ. Nipah-virus encephalitis – investigation of a new infection. Lancet. 1999;354(9186):1222-3.
8. Chua KB. Epidemiology, surveillance and control of Nipah virus infections in Malaysia. Malaysian J Pathol. 2010;2(32):69-73.
9. Johara MY, Field H, Rashdi AM, et al. Nipah virus infection in bats (order Chiroptera) in Peninsular Malaysia. Emerg Infect Dis. 2001;7(3):439-41.
10. Chua KB, Bellini WJ, Rota PA, et al. Nipah virus: a recently emergent deadly paramyxovirus. Science.
11. ;5470(288):1432-5.
12. Chua KB, Goh KJ, Wong KT, et al. Fatal encephalitis due to Nipah virus among pig-farmers in Malaysia. Lancet. 1999;9186(354):1257-9.
13. Mounts AW, Kaur H, Parashar UD, et al. A cohort study of health care workers to assess nosocomial transmissibility of Nipah virus, Malaysia, 1999. J Infect Dis. 2001;183(5):810-13.
14. Ali R, Mounts AW, Parashar UD, et al. Nipah virus infection among military personnel involved in pig culling during an outbreak of encephalitis in Malaysia, 1998–1999. Emerg Infect Dis. 2001;7(4):759-61.
15. Harcourt BH, Lowe L, Tamin A., et al. Genetic characterization of Nipah virus, Bangladesh, in 2004. Emerg Infect Dis. 2005;11(10):1594-7.
16. Maisner A, Neufeld J, Weingartl H. Organ- and endotheliotropism of Nipah virus infections in vivo and in vitro. Thromb Haemost. 2009;102:1014-23.
17. Geisbert TW, Daddario-DiCaprio KM, Hickey AC, et al. Development of acute and highly pathogenic nonhuman primate model of Nipah virus infection. PLOS ONE. 2010;5(5):article ID e10690.
18. Rahman SA, Hassan L, Epstein JH, et al. Risk factor for Nipah virus infection among Pteropid bats Peninsular Malaysia. Emerg Infect Dis. 2013;19(1):51-60.
19. Aljofan M. Hendra and Nipah infection: emerging paramyxoviruses. Virus Res. 2013;177(2):119-26.
20. Arankalle VA, Bandyopadhyay BT, Ramdasi AY, et al. Genomic Characterization of Nipah virus, West Bengal, India. Emerg Infect Dis. 2011;17(5):907-9.
21. Lo MK, Lowe L, Hummel KB, et al. Characterization of Nipah virus from outbreaks in Bangladesh, 2008–2010. Emerg Infect Dis. 2012;18(2):248-55.
22. AbuBakar S, Chang L-Y, Ali A.R.M, et al. Isolation and molecular identification of Nipah virus from pigs. Emerg Infect Dis. 2004;10(12):2228-30.
23. Epstein JH, Prakash V, Smith С.S., et al. Henipavirus infection in fruit bats (Pteropus giganteus), India. Emerg Infect Dis. 2008;14(8):1309-11.
24. Luby SP, Rahman M, Hossain MJ, et al. Foodborne transmission of Nipah virus, Bangladesh. Emerg Infect. Dis. 2006;12(12):1888-95.
25. Rockx B, Bossart KN, Feldmann F, et al. A novel model of lethal Hendra virus infection in African green monkeys and effectiveness of ribavirin trearment. J Virol. 2010;19(84):9831-9.
26. Chong HT, Kamarulzaman A, Tan CT, et al. Treatment of acute Nipah encephalitis with ribavirin. Ann Neurol. 2001;49(6):810-13.
27. Marianneau P, Guillaume V, Wong KT, et al. Experimental infection of squirrel monkeys with Nipah virus. Emerg Infect Dis. 2010;16(3):507-10.
28. Clayton BA, Middleton D, Bergfeld J, et al. Transmission routes for Nipah virus from Malaysia and Bangladesh. Emerg Infect Dis. 2012;18(12):1983-93.
29. Chadha MS, Comer JA, Lowe L, et al. Nipah virus-associated encephalitis outbreak, Siliguri, India. Emerg Infect Dis. 2006;12(2):235-40.
30. Olson JG, Rupprecht C, Rollin PE., et al. Antibodies to Nipah-like virus in bats (Pteropus lylei), Cambodia. Emerg Infect Dis. 2002;8(9):987-8.
31. Reynes JM, Counor D, Ong S, et al. Nipah virus in Lyle’s flying foxes, Cambodia. Emerg Infect Dis. 2005;11(7):1042-7.
32. Sendow I, Ratnawati A, Taylor T, et al. Nipah virus in the fruit bat Pteropus vampyrus in Sumatera, Indonesia. PLOS ONE. 013;8(7):e69544.doi:10.1371/journal.pone0069544.
33. Li Y, Wang J, Hickey A, et al. Antibodies to Nipah or Nipah-like viruses in bats, China. Emerg Infect Dis.
34. ;14(12):1974-6.
35. Wacharapluesadee S, Lumlertdacha B, Boongird K., et al. Bat Nipah virus, Thailand. Emerg Infect Dis. 2005;11(12):1949-51.
36. Hasebe F, Thuy NT, Inoue S, et al. Serologic evidence of Nipah virus infection in bats, Vietnam. Emerg Infect Dis. 2012;18(3):536-7.
37. Montgomery JM, Hossain MJ, Gurley E, et al. Risk factors for Nipah virus encephalitis in Bangladesh. Emerg Infect Dis. 2008;14(10):1526-32.
38. Luby SP, Hossain MJ, Gurley ES, et al. Reccurent zoonotic transmission of Nipah virus into humans, Bangladesh, 2001–2007. Emerg Infect Dis. 2009;15(8):1229-35.
39. Epstein JH, Rahman SA, Zambriski JA, et al. Feral cats and risk for Nipah virus transmission. Emerg Infect Dis. 2006;12(7):1178-9.
40. Mills JN, Alim ANM, Bunning ML, et al. Nipah virus infection in dogs, Malaysia, 1999. Emerg Infect Dis. 2009;15(6):950-52.
41. Goh KJ, Tan CT, Chew NK, et al. Clinical features of Nipah virus encephalitis among pig farmers in Malaysia. N Engl J Med. 2000;342(17):1229-35.
42. Sazzad HMS, Hossain MJ, Gurley ES, et al. Nipah virus infection outbreak with nosocomial and corpseto-human transmission, Bangladesh. Emerg Infect Dis. 2013;19(2):2010-17.
43. Hsu VP, Hossain MJ, Parashar UD, et al. Nipah virus encephalitis reemergence, Bangladesh. Emerg Infect Dis. 2004;10(12):2082-7.
44. Gurley ES, Montgomery JM, Hossain MJ, et al. Personto-person transmission of Nipah virus in a Bangladeshi community. Emerg Infect Dis. 2007;13(7):1031-7.
45. Hossain MJ, Gurley ES, Montgomery JM, et al. Clinical presentation of Nipah virus infection in Bangladesh. Clin Infect Dis. 2008;46(7):977-84.
46. Mathieu C, Pohl C, Szecsi J, et al. Nipah virus uses leukocytes for efficient dissemination within a host. J Virol. 2011;85(15):7863-71.
47. Escaffre O, Borisevich V, Rockx В. Pathogenesis of Hendra and Nipah virus infection in humans. J Infect Dev Ctries. 2013;7(4);308-11.
48. Wong KT, Shieh WJ, Kumar S, et al. Nipah virus infection: pathology and pathogenesis of an emerging paramyxoviral zoonosis. Am J Pathol. 2002;161(6):2153-67.
49. Sejvar JJ, Hossain J, Saha SK, et al. Long-term neurological and functional outcome of Nipah virus infection. Ann Neurol. 2007;62(3):235-42.
50. Paton NI, Leo YS, Zaki SR, et al. Outbreak of Nipah virus infection among abattoir workers in Singapore. Lancet. 1999;354(9186):1253-6.
51. Bolevich S.B., Voynov V.A. Molecular mechanisms in the pathology of humans: Guidelines for physicians. Moscow: Medical information agency, 2012. P. 65-131 (in Russian).
52. Lukin E.P., Vorobyov A.A., Makhlay A.A. Vestnik Rossiyskoy Akademii meditsinskikh nauk. 1999;12:7-13 (in Russian).
53. Simbirtsev A.S. Meditsinskiy akademicheskiy zhurnal. 2013;13(3):18-41 (in Russian).
54. Lam SK, Chua KB. Nipah virus encephalitis outbreak in Malaysia. Clin Infect Dis. 2002;34(suppl.2):48-51.
55. Harit AK, Ichhpujani RL, Gupta S, et al. Nipah/Hendra virus outbreak in Siliguri, West Bengal, India in 2001. Indian J Med Res. 2006;123(4):553-60.
56. Chua KB, Lam SK, Goh KJ, et al. The Presence of Nipah virus in respiratory secretions and urine of patients during an outbreak of Nipah virus encephalitis in Malaysia. J Infect. 2001;42(1):40-3.
57. Abdullah S, Chang L-Y, Rahmat K, et al. Late-onset Nipah virus encephalitis 11 years after initial outbreak: a case report. Neurology Asia.2012:17(1):71-4.
58. Gourie-Devi M. Clinical aspects and experience in the management of Japanese encephalitis. In: Proceedings of the National Conference on Japanese Encephalitis, November 3–4, 1982. New Delhi;1984.p.25-9.
59. Sarkari NBS, Barthwal SP, Gupta AK, et al. A clinical appraisal of two epidemics of Japanese encephalitis in eastern Uttar Pradesh. In: Proceedings of the National Conference on Japanese Encephalitis, November 3–4, 1982. New Delhi;1984.p.34-40.
Review
For citations:
Lukin E.P. Nipah Encephalitis – A Dangerous Zooanthroponosis Of Indo-Malaysian Region Of South-Еast Asia. Journal Infectology. 2014;6(3):15-26. (In Russ.) https://doi.org/10.22625/2072-6732-2014-6-3-15-26
Views:
861
.png)
.png)
Email this article 