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Clinical and laboratory description of primary invasion with Toxoplasma gondii (acute acquired toxoplasmosis)

https://doi.org/10.22625/2072-6732-2009-1-2,3-36-42

Abstract

Clinical manifestations, dynamics of biochemical and immunologic characteristics, serologic markers were studied in 91 immunocompetent patients with acute acquired toxoplasmosis. It was shown for the first time that the initial stage of acute acquired toxoplasmosis is characterized by dominating of Th-1 type of immune response, followed by develop and progress of Th-2 type. Also the second wave of specific antibodies Ig M synthesis in non-pregnant acute toxoplasmic patients was detected for the first time.

About the Authors

V. V. Vasiljev
Reseach Institute of Children Infections
Russian Federation


G. M. Ushakova
Reseach Institute of Children Infections
Russian Federation


G. A. Zhanarstanova
Reseach Institute of Children Infections
Russian Federation


S. H. Kuymchan
Saint-Petersburg Medical Academy of Post-Graduate Education
Russian Federation


A. V. Kopulova
Saint-Petersburg Medical Academy of Post-Graduate Education
Russian Federation


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For citations:


Vasiljev V.V., Ushakova G.M., Zhanarstanova G.A., Kuymchan S.H., Kopulova A.V. Clinical and laboratory description of primary invasion with Toxoplasma gondii (acute acquired toxoplasmosis). Journal Infectology. 2009;1(2,3):36-42. (In Russ.) https://doi.org/10.22625/2072-6732-2009-1-2,3-36-42

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ISSN 2072-6732 (Print)