Сlinical and epidemiological features of rotavirus infections in infants
https://doi.org/10.22625/2072-6732-2014-6-2-12-16
Abstract
Objective: to study the clinical and epidemiological characteristics, the nature of the course and outcomes of the disease in children with rotavirus mono- and mixed viral - bacterial lesions of the gastrointestinal tract.
Materials and methods: in this work the results of clinical observations of 143 patients with rotavirus infection before the age of 1 year. At the same time 69 children were diagnosed with rotavirus gastroenteritis, while 74 people. there has been a combination of rotavirus with the pathogenic microflora.
Results and conclusion: The clinical picture of combined forms of rotavirus infection differed for signs of defeat all parts of the gastrointestinal tract, inflammatory changes in the blood and coprogram. Combined damage to the intestinal mucosa and the associated inflammation conditioned a «non-smooth» during the acute period of the disease, which significantly increased the duration of treatment and hospital stay.
About the Authors
G. P. Martynova
Krasnoyarsk State Medical University named after professor V.F. Voyno-Yasenetsky, Krasnoyarsk, Russia
Russian Federation
Russian Federation
I. A. Solov`eva
Krasnoyarsk State Medical University named after professor V.F. Voyno-Yasenetsky, Krasnoyarsk, Russia
Russian Federation
Russian Federation
A. N. Alexeenko
Krasnoyarsk State Medical University named after professor V.F. Voyno-Yasenetsky, Krasnoyarsk, Russia
Russian Federation
Russian Federation
N. F. Kuznetsova
Krasnoyarsk Interdistrict Children`s Clinical Hospital № 1, Krasnoyarsk, Russia
Russian Federation
Russian Federation
A. G. Yuzhakova
Krasnoyarsk State Medical University named after professor V.F. Voyno-Yasenetsky, Krasnoyarsk, Russia
Russian Federation
Russian Federation
References
1. Belan, Y.B. Primeneniye enterosorbentov v kompleksnoy terapii mono- i mikstvariantov rotavirusnoy infektsii u detey /Y.B. Belan, N.A. Polyanskaya // Pediatricheskaya farmakologiya. – 2008. - № 4. – S. 112–114.
2. Denisyuk, N.B. Rotavirusnaya infectsiya u detey: mono- i sochetannyye formy, osobennosti kliniki i techeniya / N.B. Denisyuk // Zhurnal infektologii. – 2012. - № 4. – S. 20–24.
3. Klinika, epidemiologiya i profilaktika rotavirusnoy infektsii: metodicheskiye rekomendatsii / pod. red. akademika RAMN prof. Y.V. Lobzina. – SPb. : NIIDI, 2013. – 48s.
4. Mazankova, L.N. Rotavirusnaya infektsiya u detey rannego vozrasta: obosnovaniye probioticheskoy korrektsii. /L.N. Mazankova, G.Y. Yakovleva, M.D. Ardatskaya // Detskiye infektsii. – 2011. – №2. – S. 52–56.
5. Martynova, G.P. Izmeneniye metabolicheskoy aktivnosti mikroflory kishechnika pri rotavirusnoy infektsii u detey /G.P. Martynova, N.V. Kogan // Sib. Med. obozreniye. – 2008. – № 5. – S. 54–59
6. Burden of hospitalizations due to Rotavirus infection in Emilia Romagna, Italy / G. Gabutti [et al.] // Acta Biomed – 2007. – № 78. – P. 176–181.
7. Givon-Lavi, N. Comparison between two severity scoring scales commonly used in the evaluation of rotavirus gastroenteritis in children / N. Givon-Lavi , D. Greenberg, R. Dagan // Vaccine. – 2008. – № 26. – P. 5798–5801.
8. Diarrhea with Rotavirus in Children / C. Singer [et al.] //Current Health Sciences J. – 2010. – № 36. – P. 5698–5700.
Review
For citations:
Martynova G.P., Solov`eva I.A., Alexeenko A.N., Kuznetsova N.F., Yuzhakova A.G. Сlinical and epidemiological features of rotavirus infections in infants. Journal Infectology. 2014;6(2):12-16. (In Russ.) https://doi.org/10.22625/2072-6732-2014-6-2-12-16
Views:
757
.png)
.png)
Email this article 