Clinical and epidemiological characteristic viral diarrhea in children
https://doi.org/10.22625/2072-6732-2014-6-1-60-66
Abstract
Viral intestinal infections play an important role in infectious diseases in children of different ages.
Aim of this study was to investigate the etiological structure and characteristics of viral diarrhea in hospitalized children in 2009–2013.
Materials and Methods: 5535 children’s medical histories were analyzed, in which algorithm survey polymerase chain reaction using primers production «AmpliSens ® Rotavirus / Norovirus / Astrovirus-FL» or «OCI screen AmpliSens ® -FL», «AmpliSens ® Enterovirus-FL» production «InterLabService» (Moscow) was included.
Results: we found that with using the polymerase chain reaction etiologic diagnosis was deciphered in 3241 cases (59,8%) and the part of diarrhea of viral genesis of decrypted acute intestinal infections was 77,35 %. Results have shown that the virus diarrhea predominantly affects children under 3 years old (45%). Revealed the prevalence of rotavirus infection (40,44%) also a high proportion of norovirus gastroenteritis (21,18%) have been founded. We found that rotavirus have the first place in importance in the age group of children up to 6 years (56%); however in patients of school age the first place was the norovirus (45,2%). The incidence of rotavirus infection remained high throughout the study period (44,6-58,9%), incidence of norovirus gastroenteritis increased from 24 % in 2010 to 32% in 2012 . In most cases (82%) of viral gastroenteritis was moderate, major complication was dehydration syndrome of 1–2 stage.
Conclusion: results have proved that using of modern methods of diagnosis help to decrypt at least 60% of cases of infectious diarrhea, and the main etiological agents are rotaviruses and noroviruses . Our results are fully consistent with the data on the epidemiology in foreign sources of acute intestinal infections in children prior to mass vaccination rotavirus.
About the Authors
A. M. Lukjanova
Science Research Institute of Children’s Infections of FMBA of Russia, Saint-Petersburg, Russia
Russian Federation
Russian Federation
M. K. Bekhtereva
Science Research Institute of Children’s Infections of FMBA of Russia, Saint-Petersburg, Russia
Russian Federation
Russian Federation
N. N. Ptichnikova
Science Research Institute of Children’s Infections of FMBA of Russia, Saint-Petersburg, Russia
Russian Federation
Russian Federation
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Review
For citations:
Lukjanova A.M., Bekhtereva M.K., Ptichnikova N.N. Clinical and epidemiological characteristic viral diarrhea in children. Journal Infectology. 2014;6(1):60-66. (In Russ.) https://doi.org/10.22625/2072-6732-2014-6-1-60-66
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