Condition peroxidations and antioxidative systems with children at the influenza a h1n1 pdm09
https://doi.org/10.22625/2072-6732-2014-6-1-29-34
Abstract
The objective: to study a role peroxidation of lipids and antioxidative system at children at influenza А H1N1pdm09.
Materials and methods: research prooxidatic and antioxidatic activity of blood at 114 children with an uncomplicated current of influenza A H1N1pdm09 and at 87 children with a pneumonia associated with a virus of influenza A H1N1pdm09 is carried out.
Results of research: it is established, that uncomplicated forms of influenza A H1N1pdm09 at children’s age are accompanied by depression of antioxidatic protection and appreciable intensifying of processes peroxidations of lipids, depending on gravity of a clinical current of an infection. At the complicated current of influenza A H1N1pdm09 a pneumonia processes peroxidations of lipids proceed more intensively, especially at a serious current of pathological process.
Conclusion: development of oxidising stress with prevalence of oxidizers is one of key pathogenetic links of formation of the serious and complicated forms of influenza A H1N1pdm09 at children.
References
1. Leneva IA. Rossiyskiy medicinskiy zhurnal. 2010; 9: 597-00 (in Russian).
2. Richard J. The role of oseltamivir in the treatment and prevention of influenza in children. Expert. Opin. Drug Metab. and Toxicol. 2007; 5: 755–67.
3. Gendon YuZ. Zhurnal mikrobiologii, epidemiologii i immunobiologii. 2006; 3: 109–18 (in Russian).
4. L'vov DK. Zhurnal mikrobiologii, epidemiologii i immunobiologii. 2008; 5: 96–00 (in Russian).
5. Chuchalin AG. Pul'monologiya. 2010. Pril.: 3–8 (in Russian).
6. Avdeev SN. Pul'monologiya i allergologiya. 2010; 4: 2–10 (in Russian).
7. Oxidising stress : pathological conditions and diseases / Men'schikova E.B. [i dr]. Moskow, ARTA, 2008 (in Russian).
8. Uchaikin VF. Diagnostika, treatment and preventive maintenance of a flu and acute respiratory infections at children. Moskow, 2001(in Russian).
9. Extramural pneumonia at children : prevalence, diagnostics, treatment and preventive maintenance / A.G. Chuchalin [i dr.]. Moskow, Original-maket, 2011 (in Russian).
10. Bradley JS, Byington CL, Shah SS, et al. The management of community-acquired pneumonia in infants and children older than 3 months of age: clinical practice guidelines by the Pediatric Infectious Diseases Society and Infectious Diseases Society of America. Clin. Infect. Dis. – Aduance Access published August 30, 2011: 1–5.
11. Diagnostic value of leukocytic tests. Definition biocide leucocytes. D.N. Mayanskiy [i dr.]. – Novosibirsk, 1996 (in Russian).
12. Zhuravlev A.I. Superweak a luminescence of blood serum and its value in complex diagnostics / A.I. Zhuravlev, A.I. Zhuravleva. Moskow, Medicina, 1975 (in Russian).
13. Kulikov V.Yu. Medicina i obrazovanie v Sibiri : elektronniy nauchniy zhurnal. 2009; №4. – Rezhim dostupa : http://www.ngmu.ru/cozo/mos/article/text_full.php?id=368) (in Russian).
14. Shanin Yu.N. Antioxidatic therapy in clinical practice (a theoretical substantiation and carrying out strategy) / Yu.N. Shanin, V.Yu. Shanin, E.V. Zinoviev. Sankt-Peterburg: ELBI-SPb., 2003 (in Russian).
Review
For citations:
Miromanova N.A. Condition peroxidations and antioxidative systems with children at the influenza a h1n1 pdm09. Journal Infectology. 2014;6(1):29-34. (In Russ.) https://doi.org/10.22625/2072-6732-2014-6-1-29-34