Preview

Journal Infectology

Advanced search

PostCOVID: cardiac rhythm and conduction disorders in children. Interim results of a longitudinal study

https://doi.org/10.22625/2072-6732-2025-17-4-103-106

Abstract

Goal. To study the long-term effect of the SARS-CoV-2 virus on the cardiovascular system in children of the Smolensk region.
Materials and methods. Holter ECG monitoring for children aged 1 month to 18 years who suffered from mild or moderate COVID-19 within 3 to 12 months after discharge.
Results. Sinus tachycardia unrelated to physical activity was recorded in 35%, sinus bradycardia - 25,9%. Non-sinus rhythm was observed in 19 children. 125 children had atrial extrasystoles. Ventricular extrasystoles were registered in 35% (single – 18,7%, by type of bigeminia – 17,9%, trigeminia – 9,4% and quadrigeminia – 1,8%). Among the cardiac conduction disorders, the leading position was occupied by atrioventricular blockages of 1–3 degrees, conduction disorders along the right and left legs of the Gis bundle, as well as their complete and incomplete blockages. Rhythm pauses were observed in 4,1% of cases, very low HRV was observed in 9,7% and QTc prolongation was observed in 40.2% of children, respectively.
Conclusion. Cardiovascular lesions are one of the most central problems of post-covid. Various cardiac arrhythmias and conduction disorders have been recorded, and their frequency has been shown in pediatric patients aged 1 month to 18 months.

About the Authors

V. V. Sokolovskaja
Smolensk State Medical University
Russian Federation

Smolensk



A. A. Litvinova
Smolensk State Medical University
Russian Federation

Smolensk



A. V. Krikova
Smolensk State Medical University
Russian Federation

Smolensk



R. S. Kozlov
Smolensk State Medical University
Russian Federation

Smolensk



References

1. Mallhi T. H. et al. Atypical complications during the course of COVID-19: a comprehensive review // Medicina. – 2024. – Т. 60. – №. 1. – С. 164.

2. Gupta A. et al. Extrapulmonary manifestations of COVID-19 //Nature medicine. – 2020. – Т. 26. – №. 7. – С. 1017-1032.

3. Coopersmith C. M. et al. The surviving sepsis campaign: research priorities for coronavirus disease 2019 in critical illness //Critical care medicine. – 2021. – Т. 49. – №. 4. – С. 598-622.

4. Ahmadi A. et al. Cardiovascular Complications in Children Post COVID-19: A Systematic Review //Advanced Biomedical Research. – 2024. – Т. 13. – №. 1. – С. 94.

5. Craver R. et al. Fatal eosinophilic myocarditis in a healthy 17-year-old male with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2c) //Fetal and pediatric pathology. – 2020. – Т. 39. – №. 3. – С. 263-268.

6. Litvinova A. A. i dr. Analiz osnovnyh jelektrokardiograficheskih patternov u detej s COVID-19 v ostryj period zabolevanija po dannym za 2021-2022 gg // Vestnik Smolenskoj gosudarstvennoj medicinskoj akademii. – 2022. – T. 21. – №. 4. – S. 93-98.

7. Simpson M, Collins C, Nash DB, Panesar LE, Oster ME. Coronavirus Disease 2019 Infection in Children with Pre-Existing Heart Disease. J Pediatr. 2020;227:302–7. doi: 10.1016/j.jpeds.2020.07.069

8. Rodriguez-Gonzalez M. et al. Cardiovascular impact of COVID-19 with a focus on children: A systematic review //World journal of clinical cases. – 2020. – Т. 8. – №. 21. – С. 5250.

9. Makarov L. M. et al. National Russian guidelines on application of the methods of Holter monitoring in clinical practice //Russian journal of cardiology. – 2014. – №. 2. – С. 6-71

10. Arsent’eva R. H. Sindrom udlinennogo intervala QT // Vestnik sovremennoj klinicheskoj mediciny. – 2012. – T. 5. – №. 3. – S. 69-73.

11. Epstein R., Liberman L., Silver E. S. Long-Term FollowUp of Second-Degree Heart Block in Children //Pediatric Cardiology. – 2023. – Т. 44. – №. 7. – С. 1529-1535.

12. Balas R. B., Meliț L. E., Mărginean C. O. COVID-19 and Cardiac Implications—Still a Mystery in Clinical Practice // Reviews in Cardiovascular Medicine. – 2023. – Т. 24. – №. 5. – С. 125.

13. Lazea C., Șufană C., Popa A. Case 13: WPW Syndrome with PSVT Episodes in COVID Pandemics //Pediatric Holter Monitoring: A Case-based Approach. – Cham : Springer Nature Switzerland, 2025. – С. 197-208.

14. Sokolovskaja V. V. Vlijanie COVID-19 na serdechnososudistuju sistemu: obzor literatury / V. V. Sokolovskaja, A. A. Litvinova // Pediatrija. Vostochnaja Evropa. – 2024. – T. 12, № 1. – S. 64-77.

15. Camkiran V., Ozden O., Atar I. Long-term follow-up of patients with Brugada syndrome: Foremost risk factors associated with overall arrhythmic events //Medicine. – 2024. – Т. 103. – №. 18. – С. e37990.

16. Zhang B. et al. Cardiovascular post-acute sequelae of SARS-CoV-2 in children and adolescents: cohort study using electronic health records //Nature communications. – 2025. – Т. 16. – №. 1. – С. 3445

17. Notarte K. I. et al. Autoantibodies in COVID-19 survivors with post-COVID symptoms: a systematic review //Frontiers in immunology. – 2024. – Т. 15. – С. 1428645.

18. Boever J. et al. Long-term microvascular changes in multisystem inflammatory syndrome in children //JAMA pediatrics. – 2024. – Т. 178. – №. 3. – С. 304-306.

19. Zuo W. et al. The persistence of SARS-CoV-2 in tissues and its association with long COVID symptoms: a cross-sectional cohort study in China //The Lancet Infectious Diseases. – 2024. – Т. 24. – №. 8. – С. 845-855.

20. Mangalamoorthy J. et al. Cardiac manifestations of pediatric COVID-19 and multisystem inflammatory syndrome in children //Progress in Pediatric Cardiology. – 2025. – Т. 76. – С. 101.


Review

For citations:


Sokolovskaja V.V., Litvinova A.A., Krikova A.V., Kozlov R.S. PostCOVID: cardiac rhythm and conduction disorders in children. Interim results of a longitudinal study. Journal Infectology. 2025;17(4):101-106. (In Russ.) https://doi.org/10.22625/2072-6732-2025-17-4-103-106

Views: 133

JATS XML


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2072-6732 (Print)