<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">jofin</journal-id><journal-title-group><journal-title xml:lang="ru">Журнал инфектологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal Infectology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-6732</issn><publisher><publisher-name>IPO “АIDSSPbR"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22625/2072-6732-2025-17-4-103-106</article-id><article-id custom-type="elpub" pub-id-type="custom">jofin-1895</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Оригинальное исследование</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Original Research</subject></subj-group></article-categories><title-group><article-title>Постковид: нарушения ритма и проводимости сердца у детей. Промежуточные результаты лонгитюдного исследования</article-title><trans-title-group xml:lang="en"><trans-title>PostCOVID: cardiac rhythm and conduction disorders in children. Interim results of a longitudinal study</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соколовская</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sokolovskaja</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Соколовская Влада Вячеславовна – заведующая кафедрой инфекционных болезней у детей, к.м.н., доцент, главный внештатный специалист по инфекционным болезням у детей Министерства здравохранения Смоленской области по здравоохранению </p><p>Смоленск</p></bio><bio xml:lang="en"><p>Smolensk</p></bio><email xlink:type="simple">vlada-vs@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Литвинова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Litvinova</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Литвинова Александра Алексеевна – клинический ординатор 2-го года кафедры инфекционных болезней у детей </p><p>Смоленск</p></bio><bio xml:lang="en"><p>Smolensk</p></bio><email xlink:type="simple">Alexa5582@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Крикова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Krikova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Крикова Анна Вячеславовна – заведующий кафедрой управления и экономики фармации, д.фарм.н., доцент </p><p>Смоленск</p></bio><bio xml:lang="en"><p>Smolensk</p></bio><email xlink:type="simple">anna.krikova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Козлов</surname><given-names>Р. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kozlov</surname><given-names>R. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Козлов Роман Сергеевич – ректор, д.м.н., член-корреспондент РАН </p><p>Смоленск</p></bio><bio xml:lang="en"><p>Smolensk</p></bio><email xlink:type="simple">roman.kozlov@antibiotic.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Смоленский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Smolensk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>18</day><month>12</month><year>2025</year></pub-date><volume>17</volume><issue>4</issue><fpage>101</fpage><lpage>106</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Соколовская В.В., Литвинова А.А., Крикова А.В., Козлов Р.С., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Соколовская В.В., Литвинова А.А., Крикова А.В., Козлов Р.С.</copyright-holder><copyright-holder xml:lang="en">Sokolovskaja V.V., Litvinova A.A., Krikova A.V., Kozlov R.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.niidi.ru/jofin/article/view/1895">https://journal.niidi.ru/jofin/article/view/1895</self-uri><abstract><p>Цель: изучение долгосрочного влияния вируса SARSCoV-2 на сердечно-сосудистую систему у детей Смоленской области. Материалы и методы: проведение Холтеровского мониторирования ЭКГ детям в возрасте от 1 месяца до 18 лет, перенесших COVID-19 легкой или средней степени тяжести, в интервале от 3 до 12 месяцев после выписки. Результаты: синусовая тахикардия, не связанная с физической нагрузкой, зафиксирована у 35% детей, синусовая брадикардия – у 25,9%. Несинусовый ритм отмечался у 19 детей. У 125 детей отмечались предсердные экстрасистолы. Желудочковые экстрасистолы регистрировались в 35% случаев (одиночные – 18,7%, по типу бигеминии – 17,9%, тригеминии – 9,4% и квадригеминии – 1,8%). Среди нарушений проводимости сердца лидирующую позицию занимали: атриовентрикулярные блокады 1–3 степеней, нарушения проводимости по правой и левой ножкам пучка Гиса, а также их полные и неполные блокады. Паузы ритма отмечались в 4,1% случаев, удлинение QTc – у 40,2% детей соответственно. Заключение: сердечно-сосудистые поражения являются одной из самых центральных проблем постковида. Зафиксированы различные нарушения ритма и проводимости сердца, показана частота их встречаемости у детей в возрасте от 1 месяца до 18 месяцев.</p></abstract><trans-abstract xml:lang="en"><p>Goal. To study the long-term effect of the SARS-CoV-2 virus on the cardiovascular system in children of the Smolensk region. Materials and methods. Holter ECG monitoring for children aged 1 month to 18 years who suffered from mild or moderate COVID-19 within 3 to 12 months after discharge. Results. Sinus tachycardia unrelated to physical activity was recorded in 35%, sinus bradycardia - 25,9%. Non-sinus rhythm was observed in 19 children. 125 children had atrial extrasystoles. Ventricular extrasystoles were registered in 35% (single – 18,7%, by type of bigeminia – 17,9%, trigeminia – 9,4% and quadrigeminia – 1,8%). Among the cardiac conduction disorders, the leading position was occupied by atrioventricular blockages of 1–3 degrees, conduction disorders along the right and left legs of the Gis bundle, as well as their complete and incomplete blockages. Rhythm pauses were observed in 4,1% of cases, very low HRV was observed in 9,7% and QTc prolongation was observed in 40.2% of children, respectively. Conclusion. Cardiovascular lesions are one of the most central problems of post-covid. Various cardiac arrhythmias and conduction disorders have been recorded, and their frequency has been shown in pediatric patients aged 1 month to 18 months.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>COVID-19</kwd><kwd>постковид</kwd><kwd>сердечно-сосудистая система</kwd><kwd>аритмии</kwd><kwd>блокады</kwd><kwd>дети</kwd></kwd-group><kwd-group xml:lang="en"><kwd>COVID-19</kwd><kwd>post-COVID</kwd><kwd>cardiovascular system</kwd><kwd>arrhythmias</kwd><kwd>blockades</kwd><kwd>children</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Mallhi T. H. et al. Atypical complications during the course of COVID-19: a comprehensive review //Medicina. – 2024. – Т. 60. – №. 1. – С. 164.</mixed-citation><mixed-citation xml:lang="en">Mallhi T. H. et al. Atypical complications during the course of COVID-19: a comprehensive review // Medicina. – 2024. – Т. 60. – №. 1. – С. 164.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Gupta A. et al. Extrapulmonary manifestations of COVID-19 //Nature medicine. – 2020. – Т. 26. – №. 7. – С. 1017-1032.</mixed-citation><mixed-citation xml:lang="en">Gupta A. et al. Extrapulmonary manifestations of COVID-19 //Nature medicine. – 2020. – Т. 26. – №. 7. – С. 1017-1032.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Coopersmith C. M. et al. The surviving sepsis campaign: research priorities for coronavirus disease 2019 in critical illness //Critical care medicine. – 2021. – Т. 49. – №. 4. – С. 598-622.</mixed-citation><mixed-citation xml:lang="en">Coopersmith C. M. et al. The surviving sepsis campaign: research priorities for coronavirus disease 2019 in critical illness //Critical care medicine. – 2021. – Т. 49. – №. 4. – С. 598-622.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Ahmadi A. et al. Cardiovascular Complications in Children Post COVID-19: A Systematic Review //Advanced Biomedical Research. – 2024. – Т. 13. – №. 1. – С. 94.</mixed-citation><mixed-citation xml:lang="en">Ahmadi A. et al. Cardiovascular Complications in Children Post COVID-19: A Systematic Review //Advanced Biomedical Research. – 2024. – Т. 13. – №. 1. – С. 94.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Craver R. et al. Fatal eosinophilic myocarditis in a healthy 17-year-old male with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2c) //Fetal and pediatric pathology. – 2020. – Т. 39. – №. 3. – С. 263-268.</mixed-citation><mixed-citation xml:lang="en">Craver R. et al. Fatal eosinophilic myocarditis in a healthy 17-year-old male with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2c) //Fetal and pediatric pathology. – 2020. – Т. 39. – №. 3. – С. 263-268.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Литвинова А.А. и др. Анализ основных электрокардиографических паттернов у детей с COVID-19 в острый период заболевания по данным за 2021-2022 гг // Вестник Смоленской государственной медицинской академии. – 2022. – Т. 21. – №. 4. – С. 93-98.</mixed-citation><mixed-citation xml:lang="en">Litvinova A. A. i dr. Analiz osnovnyh jelektrokardiograficheskih patternov u detej s COVID-19 v ostryj period zabolevanija po dannym za 2021-2022 gg // Vestnik Smolenskoj gosudarstvennoj medicinskoj akademii. – 2022. – T. 21. – №. 4. – S. 93-98.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Simpson M, Collins C, Nash DB, Panesar LE, Oster ME. Coronavirus Disease 2019 Infection in Children with Pre-Existing Heart Disease. J Pediatr. 2020;227:302–7. doi: 10.1016/j.jpeds.2020.07.069</mixed-citation><mixed-citation xml:lang="en">Simpson M, Collins C, Nash DB, Panesar LE, Oster ME. Coronavirus Disease 2019 Infection in Children with Pre-Existing Heart Disease. J Pediatr. 2020;227:302–7. doi: 10.1016/j.jpeds.2020.07.069</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Rodriguez-Gonzalez M. et al. Cardiovascular impact of COVID-19 with a focus on children: A systematic review //World journal of clinical cases. – 2020. – Т. 8. – №. 21. – С. 5250.</mixed-citation><mixed-citation xml:lang="en">Rodriguez-Gonzalez M. et al. Cardiovascular impact of COVID-19 with a focus on children: A systematic review //World journal of clinical cases. – 2020. – Т. 8. – №. 21. – С. 5250.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Makarov L. M. et al. National Russian guidelines on application of the methods of Holter monitoring in clinical practice //Russian journal of cardiology. – 2014. – №. 2. – С. 6-71</mixed-citation><mixed-citation xml:lang="en">Makarov L. M. et al. National Russian guidelines on application of the methods of Holter monitoring in clinical practice //Russian journal of cardiology. – 2014. – №. 2. – С. 6-71</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Арсентьева Р. Х. Синдром удлиненного интервала QT //Вестник современной клинической медицины. – 2012. – Т. 5. – №. 3. – С. 69-73.</mixed-citation><mixed-citation xml:lang="en">Arsent’eva R. H. Sindrom udlinennogo intervala QT // Vestnik sovremennoj klinicheskoj mediciny. – 2012. – T. 5. – №. 3. – S. 69-73.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Epstein R., Liberman L., Silver E. S. Long-Term FollowUp of Second-Degree Heart Block in Children //Pediatric Cardiology. – 2023. – Т. 44. – №. 7. – С. 1529-1535.</mixed-citation><mixed-citation xml:lang="en">Epstein R., Liberman L., Silver E. S. Long-Term FollowUp of Second-Degree Heart Block in Children //Pediatric Cardiology. – 2023. – Т. 44. – №. 7. – С. 1529-1535.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Balas R. B., Meliț L. E., Mărginean C. O. COVID-19 and Cardiac Implications—Still a Mystery in Clinical Practice //Reviews in Cardiovascular Medicine. – 2023. – Т. 24. – №. 5. – С. 125.</mixed-citation><mixed-citation xml:lang="en">Balas R. B., Meliț L. E., Mărginean C. O. COVID-19 and Cardiac Implications—Still a Mystery in Clinical Practice // Reviews in Cardiovascular Medicine. – 2023. – Т. 24. – №. 5. – С. 125.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Lazea C., Șufană C., Popa A. Case 13: WPW Syndrome with PSVT Episodes in COVID Pandemics //Pediatric Holter Monitoring: A Case-based Approach. – Cham : Springer Nature Switzerland, 2025. – С. 197-208.</mixed-citation><mixed-citation xml:lang="en">Lazea C., Șufană C., Popa A. Case 13: WPW Syndrome with PSVT Episodes in COVID Pandemics //Pediatric Holter Monitoring: A Case-based Approach. – Cham : Springer Nature Switzerland, 2025. – С. 197-208.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Соколовская В. В. Влияние COVID-19 на сердечнососудистую систему: обзор литературы / В. В. Соколовская, А. А. Литвинова // Педиатрия. Восточная Европа. – 2024. – Т. 12, № 1. – С. 64-77.</mixed-citation><mixed-citation xml:lang="en">Sokolovskaja V. V. Vlijanie COVID-19 na serdechnososudistuju sistemu: obzor literatury / V. V. Sokolovskaja, A. A. Litvinova // Pediatrija. Vostochnaja Evropa. – 2024. – T. 12, № 1. – S. 64-77.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Camkiran V., Ozden O., Atar I. Long-term follow-up of patients with Brugada syndrome: Foremost risk factors associated with overall arrhythmic events //Medicine. – 2024. – Т. 103. – №. 18. – С. e37990.</mixed-citation><mixed-citation xml:lang="en">Camkiran V., Ozden O., Atar I. Long-term follow-up of patients with Brugada syndrome: Foremost risk factors associated with overall arrhythmic events //Medicine. – 2024. – Т. 103. – №. 18. – С. e37990.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Zhang B. et al. Cardiovascular post-acute sequelae of SARS-CoV-2 in children and adolescents: cohort study using electronic health records //Nature communications. – 2025. – Т. 16. – №. 1. – С. 3445</mixed-citation><mixed-citation xml:lang="en">Zhang B. et al. Cardiovascular post-acute sequelae of SARS-CoV-2 in children and adolescents: cohort study using electronic health records //Nature communications. – 2025. – Т. 16. – №. 1. – С. 3445</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Notarte K. I. et al. Autoantibodies in COVID-19 survivors with post-COVID symptoms: a systematic review //Frontiers in immunology. – 2024. – Т. 15. – С. 1428645.</mixed-citation><mixed-citation xml:lang="en">Notarte K. I. et al. Autoantibodies in COVID-19 survivors with post-COVID symptoms: a systematic review //Frontiers in immunology. – 2024. – Т. 15. – С. 1428645.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Boever J. et al. Long-term microvascular changes in multisystem inflammatory syndrome in children //JAMA pediatrics. – 2024. – Т. 178. – №. 3. – С. 304-306.</mixed-citation><mixed-citation xml:lang="en">Boever J. et al. Long-term microvascular changes in multisystem inflammatory syndrome in children //JAMA pediatrics. – 2024. – Т. 178. – №. 3. – С. 304-306.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Zuo W. et al. The persistence of SARS-CoV-2 in tissues and its association with long COVID symptoms: a cross-section-al cohort study in China //The Lancet Infectious Diseases. – 2024. – Т. 24. – №. 8. – С. 845-855.</mixed-citation><mixed-citation xml:lang="en">Zuo W. et al. The persistence of SARS-CoV-2 in tissues and its association with long COVID symptoms: a cross-sectional cohort study in China //The Lancet Infectious Diseases. – 2024. – Т. 24. – №. 8. – С. 845-855.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Mangalamoorthy J. et al. Cardiac manifestations of pediatric COVID-19 and multisystem inflammatory syndrome in children //Progress in Pediatric Cardiology. – 2025. – Т. 76. – С. 101784.</mixed-citation><mixed-citation xml:lang="en">Mangalamoorthy J. et al. Cardiac manifestations of pediatric COVID-19 and multisystem inflammatory syndrome in children //Progress in Pediatric Cardiology. – 2025. – Т. 76. – С. 101.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
