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Maternal factors that influence the course of HIV infection in children

https://doi.org/10.22625/2072-6732-2013-5-2-70-75

Abstract

91 pair «HIV infected pregnant women – HIV positive child» were examined. In 26% children, rapid progression of HIV infection to the development of AIDS in the first two years of life were observed. Multifactorial logistic regression model demonstrated, that independent predictors of rapid HIV-infection progression in children were horionamnionitis and fetal growth retardation during pregnancy in the mother. Sensitivity of both predictors parallel usage for forecasting of poor HIV-infection course in children was 83%, and specificity was 67%.

About the Authors

V. B. Denisenko
Rostov State Medical University, Rostov-on-Don
Russian Federation


E. N. Simovanian
Rostov State Medical University, Rostov-on-Don
Russian Federation


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Review

For citations:


Denisenko V.B., Simovanian E.N. Maternal factors that influence the course of HIV infection in children. Journal Infectology. 2013;5(2):70-75. (In Russ.) https://doi.org/10.22625/2072-6732-2013-5-2-70-75

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ISSN 2072-6732 (Print)