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Using the quantitative determination of HBsAg to predict the course of chronic hepatitis B in women during pregnancy and after childbirth

https://doi.org/10.22625/2072-6732-2013-5-2-50-54

Abstract

This study is based on the investigation of 31 HB V-infected women, which have observed at Botkin Infectious Hospital in 2012. Considerable variations of viral load in the course of pregnancy have been observed in the HB V cohort. In the course of pregnancy the HBsAg level does not vary too much. A high HBsAg HBsAg HBsAg HBsAg HBsAg level in the HB HB V cohort can be used as a predictive factor of exacerbation after delivery.

About the Authors

M. A. Belopolskaya
Clinical Infectious Diseases Hospital named by S.P. Botkin, Saint-Petersburg
Russian Federation


T. V. Volokobinskaya
Clinical Infectious Diseases Hospital named by S.P. Botkin, Saint-Petersburg
Russian Federation


S. L. Firsov
Clinical Infectious Diseases Hospital named by S.P. Botkin, Saint-Petersburg
Russian Federation


A. A. Yakovlev
Clinical Infectious Diseases Hospital named by S.P. Botkin, Saint-Petersburg
Russian Federation


References

1. Kumar, M. Virological and histological features of chronic hepatitis B virus infected asymptomatic patients with persistently normal ALT / M. Kumar [et al.] // Gastroenterology. – 2008. – № 134. – P. 1376–1384.

2. Lavanchy, D. Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures / D. Lavanchy // J. Viral. Hepat. – 2004. – № 11. – P. 97–107.

3. Комарова, А.Я. Распространенность хронических вирусных гепатитов среди населения Санкт-Петербурга / А.Я. Комарова, А.А. Яковлев // Клин. перспективы гастроэнт., гепатол. – 2012. – № 5. – С. 34–40.

4. Chu, C. Hepatitis B surface antigen seroclearance during chronic HBV infection / C. Chu, Y. Liaw // Antivir Ther. – 2010. – № 15. – P. 133–143.

5. Seeger, C. Hepatitis B virus biology / C. Seeger, W. Mason // Microbiol Mol BiolRev. – 2000. – № 64. – P. 51–68.

6. Liaw, Y. Clinical utility of hepatitis B surface antigen quantitation in patients with chronic hepatitis B: A review / Y. Liaw // Hepatology. – 2011. – № 53. – P. 2121–2129.

7. Tran, T. Management of hepatitis B in pregnancy: weighing the options / T. Tran // Cleve Clin J Med. – 2009. – № 76 (3). – P. 25–29.


Review

For citations:


Belopolskaya M.A., Volokobinskaya T.V., Firsov S.L., Yakovlev A.A. Using the quantitative determination of HBsAg to predict the course of chronic hepatitis B in women during pregnancy and after childbirth. Journal Infectology. 2013;5(2):50-54. (In Russ.) https://doi.org/10.22625/2072-6732-2013-5-2-50-54

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ISSN 2072-6732 (Print)