Effectiveness of combined antyviral therapy in children with chronic hepatitis C
https://doi.org/10.22625/2072-6732-2013-5-2-37-42
Abstract
The paper presents the results of the research on effectiveness of combined antiviral therapy conducted with pegylated interferon alpha 2b of prolonged action (Peginterferon alpha 2b at a dose of 60 mcg/m2 per week) and Rebetol (Ribavirin at a dose of 15 mg/kg per day) in 26 children with chronic viral hepatitis C aged from 3 to 17, who underwent regular medical check-ups in City Clinical Hospital № 20 named after I.S. Berzon in Krasnoyarsk. Evaluation of effectiveness of combined antiviral therapy revealed that patients with genotype 1 had an immediate virologic response in 78,5% of cases, 83,3% of patients with genotype 2, 3 had a stable virologic response.
About the Authors
G. P. Martynova
Krasnoyarsk State Medical University named after professor V.F. Voyno-Yasenetskiy, Krasnoyarsk
Russian Federation
Russian Federation
I. A. Solovyova
Krasnoyarsk State Medical University named after professor V.F. Voyno-Yasenetskiy, Krasnoyarsk
Russian Federation
Russian Federation
T. A. Zhukovskaya
City Clinical Hospital № 20 named after I.S. Berzon, Krasnoyarsk
Russian Federation
Russian Federation
A. B. Belkina
City Children Clinical Hospital № 1, Krasnoyarsk
Russian Federation
Russian Federation
Ya. A. Bogvilene
Krasnoyarsk State Medical University named after professor V.F. Voyno-Yasenetskiy, Krasnoyarsk
Russian Federation
Russian Federation
I. A. Kutishcheva
Krasnoyarsk State Medical University named after professor V.F. Voyno-Yasenetskiy, Krasnoyarsk
Russian Federation
Russian Federation
S. V. Evreimova
City Children Clinical Hospital № 1, Krasnoyarsk
Russian Federation
Russian Federation
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Review
For citations:
Martynova G.P., Solovyova I.A., Zhukovskaya T.A., Belkina A.B., Bogvilene Ya.A., Kutishcheva I.A., Evreimova S.V. Effectiveness of combined antyviral therapy in children with chronic hepatitis C. Journal Infectology. 2013;5(2):37-42. (In Russ.) https://doi.org/10.22625/2072-6732-2013-5-2-37-42
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