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Эффективность и безопасность вакцин для профилактики новой коронавирусной инфекции на основе аденовирусных векторов

https://doi.org/10.22625/2072-6732-2022-14-2-14-26

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Аннотация

В обзорной статье рассматриваются вакцины против SARS-CoV-2 на основе аденовирусных векторов, применяемые в настоящее время в мире. Описана концепция создания векторных вакцин. Представлены данные клинических исследований по эффективности и безопасности зарегистрированных аденовирусных векторных вакцин для профилактики новой коронавирусной инфекции. Подробно изложена частота развития серьезных нежелательных явлений после их применения. Помимо этого, определена клиническая эффективность векторных вакцин на изменяющиеся генотипы вируса COVID-19.

В обзоре проанализированы данные литературы о безопасности и эффективности применения векторных вакцин против коронавирусной инфекции.

Используемые в настоящее время векторные вакцины против новой коронавирусной инфекции достаточно безопасны и эффективны даже по отношению к новым генотипам вируса SARS-CoV-2.

Об авторах

С. М. Харит
Детский научно-клинический центр инфекционных болезней; Санкт-Петербургский государственный педиатрический медицинский университет
Россия

Харит Сусанна Михайловна – руководитель отдела профилактики инфекционных заболеваний; профессор кафедры инфекционных заболеваний у детей ФП и ДПО; д.м.н., профессор; тел.: 8(812)234-68-55

Санкт-Петербург



И. В. Фридман
Детский научно-клинический центр инфекционных болезней
Россия

Фридман Ирина Владимировна – старший научный сотрудник отдела профилактики инфекционных заболеваний; к.м.н.; тел.: 8(812)234-68-55

Санкт-Петербург



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Рецензия

Для цитирования:


Харит С.М., Фридман И.В. Эффективность и безопасность вакцин для профилактики новой коронавирусной инфекции на основе аденовирусных векторов. Журнал инфектологии. 2022;14(2):14-26. https://doi.org/10.22625/2072-6732-2022-14-2-14-26

For citation:


Kharit S.M., Fridman I.V. Efficacy and safety of vector vaccines for the prevention of new coronavirus infection. Journal Infectology. 2022;14(2):14-26. (In Russ.) https://doi.org/10.22625/2072-6732-2022-14-2-14-26

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ISSN 2072-6732 (Print)