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Clinical case of COVID-19 course in a child with aplastic anemia

https://doi.org/10.22625/2072-6732-2022-14-1-145-151

Abstract

The problem of the non-smooth course of COVID-19 and deaths in children with severe comorbid pathology is urgent. Among all registered cases of a new coronavirus infection in the Russian Federation, children account for up to 8,6%, of which severe forms are noted, as a rule, in patients with concomitant diseases. A clinical observation of the course of a new coronavirus infection in a child with a severe form of idiopathic aplastic anemia complicated by pancytopenia is presented. COVID-19 infection caused a sharp deterioration in the child’s condition. Despite the use of modern methods of therapy, there was a rapid deterioration of clinical and laboratory parameters: an increase in febrility, respiratory failure, interstitial changes in the lungs, a decrease in oxygen saturation to 70%, hemorrhagic, anemic syndromes and multiple organ failure with the development of a fatal outcome. Aplastic anemia is a factor predisposing to the severe course of COVID-19 and contributing to an unfavorable outcome.

About the Authors

D. O. Ivanov
Saint-Petersburg State Pediatric Medical University
Russian Federation

Saint-Petersburg


Competing Interests:

Aвторы заявляют об отсутствии конфликта интересов.



Yu. V. Petrenko
Saint-Petersburg State Pediatric Medical University
Russian Federation

Saint-Petersburg



R. A. Nasyrov
Saint-Petersburg State Pediatric Medical University
Russian Federation

Saint-Petersburg



V. A. Reznik
Saint-Petersburg State Pediatric Medical University
Russian Federation

Saint-Petersburg



V. N. Timchenko
Saint-Petersburg State Pediatric Medical University
Russian Federation

Saint-Petersburg



T. A. Kaplina
Saint-Petersburg State Pediatric Medical University
Russian Federation

Saint-Petersburg



S. L. Bannova
Saint-Petersburg State Pediatric Medical University
Russian Federation

Saint-Petersburg



O. L. Krasnogorskaya
Saint-Petersburg State Pediatric Medical University
Russian Federation

Saint-Petersburg



M. B. Paneyakh
Saint-Petersburg State Pediatric Medical University
Russian Federation

Saint-Petersburg



E. P. Fedotova
Saint-Petersburg State Pediatric Medical University
Russian Federation

Saint-Petersburg



G. V. Kondratyev
Saint-Petersburg State Pediatric Medical University
Russian Federation

Saint-Petersburg



M. D. Subbotina
Saint-Petersburg State Pediatric Medical University
Russian Federation

Saint-Petersburg



M. A. Shakmaeva
Saint-Petersburg State Pediatric Medical University
Russian Federation

Saint-Petersburg



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Review

For citations:


Ivanov D.O., Petrenko Yu.V., Nasyrov R.A., Reznik V.A., Timchenko V.N., Kaplina T.A., Bannova S.L., Krasnogorskaya O.L., Paneyakh M.B., Fedotova E.P., Kondratyev G.V., Subbotina M.D., Shakmaeva M.A. Clinical case of COVID-19 course in a child with aplastic anemia. Journal Infectology. 2022;14(1):145-151. (In Russ.) https://doi.org/10.22625/2072-6732-2022-14-1-145-151

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ISSN 2072-6732 (Print)