Comparative characteristics of human betaherpesviruses 6A and 6B. A modern view on the problem
https://doi.org/10.22625/2072-6732-2021-13-3-5-18
Abstract
This review is devoted to the comparative characteristics of human herpesvirus 6A (HHV6A) and human herpesvirus 6B (HHV6B), taking into account their exogenous and endogenous (inherited chromosomally integrated) forms. The analysis of the literature data on the main interspecies differences and intraspecies features of these viruses in molecular-genetic, biological, epidemiological and clinical aspects has been consistently carried out. Modern views about HHV6A and HHV6B, including their unique inherited chromosomal-integrated form, are the basis for organizing a system of epidemiological surveillance of infections caused by these viruses, as well as developing standardized methodological approaches to differential diagnosis, treatment and specific prevention of a wide range of virus-associated diseases. The development of this direction requires a greater evidence base and intensification of joint efforts of the scientific and medical communities.
Keywords
About the Authors
M. I. Popkova
Nizhny Novgorod Scientific Research Institute of Epidemiology and Microbiology named after Academician I.N. Blokhina
Russian Federation
Competing Interests:
Russian Federation
Nizhny Novgorod.
Competing Interests:
No
O. V. Utkin
Nizhny Novgorod Scientific Research Institute of Epidemiology and Microbiology named after Academician I.N. Blokhina
Russian Federation
Competing Interests:
Russian Federation
Nizhny Novgorod.
Competing Interests:
No
D. A. Bryzgalova
Nizhny Novgorod Scientific Research Institute of Epidemiology and Microbiology named after Academician I.N. Blokhina
Russian Federation
Competing Interests:
Russian Federation
Nizhny Novgorod.
Competing Interests:
No
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Popkova M.I., Utkin O.V., Bryzgalova D.A. Comparative characteristics of human betaherpesviruses 6A and 6B. A modern view on the problem. Journal Infectology. 2021;13(3):5-18. (In Russ.) https://doi.org/10.22625/2072-6732-2021-13-3-5-18
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