Сравнительная характеристика бета-герпес-вирусов человека 6А и 6В. Современный взгляд на проблему

Представленный обзор посвящен сравнительной характеристике вируса герпеса человека 6А (ВГЧ6А) и вируса герпеса человека 6В (ВГЧ6В) с учетом их экзогенной и эндогенной (наследуемой хромосомно-интегрированной) форм. Последовательно проведен анализ литературных данных об основных межвидовых различиях и внутривидовых особенностях этих вирусов в молекулярно-генетическом, биологическом, эпидемиологическом и клиническом аспектах. Современные представления о ВГЧ6А и ВГЧ6В, в том числе их уникальной наследуемой хромосомно-интегрированной форме, являются основой для организации системы эпидемиологического надзора за инфекциями, вызываемыми данными вирусами, а также разработки стандартизованных методических подходов к дифференциальной диагностике, лечению и специфической профилактике широкого спектра вирус-ассоциированных заболеваний. Развитие данного направления требует большей доказательной базы и интенсификации совместных усилий научного и врачебного сообществ.

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