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Toxoplasmosis and liver disease: literature review and clinical observation

https://doi.org/10.22625/2072-6732-2021-13-2-135-141

Abstract

Toxoplasmosis is a widespread ubiquatorial disease. A distinctive feature of this parasitosis is the predominance of latent forms. As a rule, in people with intact immune systems, the disease is asymptomatic. Severe cases of toxoplasmosis are usually associated with immunodeficiencies. At the same time, in cases of a manifest course in immunocompetent persons, toxoplasmosis is characterized by a polymorphism of clinical manifestations with damage to almost all organs and systems. In addition to the widely reported lesions of the eyes, brain, and intrauterine infection (IUI) associated with T. gondii, there are reports of damage to the liver, heart, lungs, and even multisystem cases of visceral toxoplasmosis. The article describes a clinical observation of toxoplasma hepatitis in a child with chronic viral hepatitis C. This clinical observation demonstrates the possibility of liver damage in the structure of toxoplasmosis and confirms the significance of this parasitosis among the population of patients with liver diseases.

About the Authors

V. A. Greshnyakova
Pediatric Research and Clinical Center for Infectious Diseases
Russian Federation

Saint-Petersburg



L. G. Gorjacheva
Pediatric Research and Clinical Center for Infectious Diseases; Saint-Petersburg State Pediatric Medical University
Russian Federation

Saint-Petersburg



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Review

For citations:


Greshnyakova V.A., Gorjacheva L.G. Toxoplasmosis and liver disease: literature review and clinical observation. Journal Infectology. 2021;13(2):135-141. (In Russ.) https://doi.org/10.22625/2072-6732-2021-13-2-135-141

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ISSN 2072-6732 (Print)