Electrophysiological methods in the diagnosis of subclinical cognitive impairment in HIV-infected patients
https://doi.org/10.22625/2072-6732-2012-4-3-80-87
Abstract
With a goal of the early detection of subclinical cognitive impairment and damage of the central nervous system in the early stages HIV infection the complex neurophysiological study (electroencephalogram, cognitive evoked potentials of auditory and visual modalities, complex sensory-motor reactions, visual evoked potentials) in 20 patients with HIV infection was performed. Electrophysiological signs of subclinical cognitive impairment and non-specific subclinical involvement of central nervous system were found. Application of the complex electrophysiological study by evaluating the function of widespread neuronal networks has allowed to increasing the sensitivity of early diagnosis of subclinical cognitive impairment in HIV-infected patients in 90% of cases.
About the Authors
O. E. Gurskaya
Institute of Human Brain named by N.P. Behtereva of Russian Academy of Sciences, Saint-Petersburg
Russian Federation
Russian Federation
E. V. Galicheva
Institute of Human Brain named by N.P. Behtereva of Russian Academy of Sciences, Saint-Petersburg
Russian Federation
Russian Federation
A. V. Gaisina
Saint-Petersburg Center for the Prevention and Control of AIDS and Infectious Diseases, Saint-Petersburg
Russian Federation
Russian Federation
V. V. Rassohin
Saint-Petersburg Center for the Prevention and Control of AIDS and Infectious Diseases, Saint-Petersburg
Institute of Experimental Medicine Russian Academy of Medical Sciences, Saint-Petersburg
Russian Federation
Russian Federation
T. D. Sizova
Saint-Petersburg Center for the Prevention and Control of AIDS and Infectious Diseases, Saint-Petersburg
Institute of Experimental Medicine Russian Academy of Medical Sciences, Saint-Petersburg
Russian Federation
Russian Federation
N. A. Beliakov
Saint-Petersburg Center for the Prevention and Control of AIDS and Infectious Diseases, Saint-Petersburg
Institute of Experimental Medicine Russian Academy of Medical Sciences, Saint-Petersburg
Russian Federation
Russian Federation
S. V. Medvedev
Institute of Human Brain named by N.P. Behtereva of Russian Academy of Sciences, Saint-Petersburg
Russian Federation
Russian Federation
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Review
For citations:
Gurskaya O.E., Galicheva E.V., Gaisina A.V., Rassohin V.V., Sizova T.D., Beliakov N.A., Medvedev S.V. Electrophysiological methods in the diagnosis of subclinical cognitive impairment in HIV-infected patients. Journal Infectology. 2012;4(3):80-87. (In Russ.) https://doi.org/10.22625/2072-6732-2012-4-3-80-87
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