Metabolic processes in limfocytes of pathients with varicella zoster infections
https://doi.org/10.22625/2072-6732-2012-4-3-42-45
Abstract
Measurement of metabolic processes in lymphocytes in Varicella zoster infection showed highly increased intercellular glycolisys activity with functional cellular overload. Same time, we discovered decreased level of intensivity of first stages of TCC, that rules to lower cycle energetic efficiency and intense metabolitsaminoacides intake for TCC, guiding to high aminoacides transport to lymphocytes. Usage of succinic acid and its salts gives more substrates for TCC, increasing its energetic efficiency and lymphocytes functional activity.
About the Authors
Yu. S. Tichonova
Krasnoyarsk State Medical University named by V.F. Voino-Yasentsky
Russian Federation
Russian Federation
G. V. Bulygin
Krasnoyarsk State Medical University named by V.F. Voino-Yasentsky
Russian Federation
Russian Federation
T. Yu. Kuzmina
Krasnoyarsk State Medical University named by V.F. Voino-Yasentsky
Russian Federation
Russian Federation
E. P. Tichonova
Krasnoyarsk State Medical University named by V.F. Voino-Yasentsky
Russian Federation
Russian Federation
References
1. Булыгин, Г.В. Ме таболические основы регуляции иммунного ответа / Г.В. Булыгин, Н.И. Камзалакова, А.В. Андрейчиков. – Новосибирск: СО РАМН, 1999. – 346 с.
2. Бышевский, А.Ш. Биохимия для врача/ А.Ш. Бышевский, О.А. Терсенов. – М., 1998. – 384 с.
3. Тихонова, Е.П. Метаболические основы иммунореактивности при парентеральных гепатитах В и С / Е.П. Тихонова, Г.В. Булыгин. – Новосибирск: Наука, 2003. – 148 с.
4. Boyum, A. Separation of blood leucocytes, granulocytes and lymphocytes / A. Boyum // Tissue Antigens. – 1974. – V. 4. – P. 250–260.
5. Савченко, А.А. Высокочувствительное оп ределение активности дегидрогеназ в лимфоцитах периферической крови человека биолюминесцентным методом / А.А. Савченко, Л.Н. Сунцова // Лабораторное дело. – 1989. – № 11. – С. 23–25.
6. Реброва, О.Ю. Статистический анализ медицинских данных. Применение пакета прикладных программ Statistica / О.Ю. Реброва. – М.: Медиасфера, 2002. – 312 с.
Review
For citations:
Tichonova Yu.S., Bulygin G.V., Kuzmina T.Yu., Tichonova E.P. Metabolic processes in limfocytes of pathients with varicella zoster infections. Journal Infectology. 2012;4(3):42-45. (In Russ.) https://doi.org/10.22625/2072-6732-2012-4-3-42-45
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