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Characteristics of measles immunity in students of the pediatric faculty of a medical university

https://doi.org/10.22625/2072-6732-2020-12-4-58-64

Abstract

Objective: to evaluate the intensity of measles immunity in students of I–VI courses of the pediatric faculty of St. Petersburg State Medical University.

Materials and methods: titers of antibodies to measles virus were determined in 986 students of I–VI courses in May –June 2019. The level of measles antibodies was determined by enzyme-linked immunosorbent assay.

Results: positive (protective) titres of measles antibodies were detected in 555 people. (56.4%), the absence of measles immunity was found in 431 people. (43.6%), including 57 people. (5.8%) specific antibodies were not detected. The relationship between the level of collective immunity and the duration of the period after the last vaccination against measles was revealed.

Conclusions: in the majority of examined students (96.2%), protective titers of measles antibodies remained for 10 years after the last vaccination. Subsequently, a significant decrease in the level of measles antibodies was noted. All students who do not have a protective IgG titer are shown measles vaccination with live measles vaccine in accordance with the instructions for use. 

About the Authors

D. O. Ivanov
Saint-Petersburg State Pediatric Medical University
Russian Federation
Saint-Petersburg


V. N. Timchenko
Saint-Petersburg State Pediatric Medical University
Russian Federation
Saint-Petersburg


E. B. Pavlova
Saint-Petersburg State Pediatric Medical University
Russian Federation
Saint-Petersburg


E. V. Barakina
Saint-Petersburg State Pediatric Medical University
Russian Federation
Saint-Petersburg


T. M. Chernova
Saint-Petersburg State Pediatric Medical University
Russian Federation
Saint-Petersburg


N. V. Pavlova
Saint-Petersburg State Pediatric Medical University
Russian Federation
Saint-Petersburg


O. V. Bulina
Saint-Petersburg State Pediatric Medical University
Russian Federation
Saint-Petersburg


A. N. Nazarova
Saint-Petersburg State Pediatric Medical University
Russian Federation
Saint-Petersburg


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Review

For citations:


Ivanov D.O., Timchenko V.N., Pavlova E.B., Barakina E.V., Chernova T.M., Pavlova N.V., Bulina O.V., Nazarova A.N. Characteristics of measles immunity in students of the pediatric faculty of a medical university. Journal Infectology. 2020;12(4):58-64. (In Russ.) https://doi.org/10.22625/2072-6732-2020-12-4-58-64

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