Comparison of vezikari and clark scale for determination of of viral intestinal infections sevitity and predicting their outputs in children
https://doi.org/10.22625/2072-6732-2018-10-4-64-71
Abstract
Introduction. To assess the severity of acute gastroenteritis in children, two scales of gravity are used: a 20-point Vesicari scale and a 24-point Clark scale. However, there are significant differences between these scales and there are practically no studies comparing their effectiveness in one representative group of patients.
Material and methods: Complex clinical and laboratory examination of 143 children aged 1 to 7 with intestinal viral intestinal infections caused by rotavirus and norovirus was carried out. The severity of the patients’ condition was assessed using both Clark and Vesicary scale. Convalescences continued to be monitored for 12 months to open adverse outcomes.
Results: In assessing the severity of viral intestinal infections using Clark and Vesicari scales, there were significant
differences in children. The Vesicari scale significantly more accurately estimates the severity of intestinal infection in the acute period of the disease. At the same time, the use of the Clark scale contributes to the refinement of the prognosis for the development of post-infection gastroenterological pathology and its timely prevention.
Conclusion: There is a need to create a new scale of universal assessment of the severity of viral intestinal infections that combines the advantages of both scales.
About the Authors
K. D. Ermolenko
Pediatric Research and Clinical Center for Infectious Diseases, Saint-Petersburg
Russian Federation
Russian Federation
N. V. Gonchar
Pediatric Research and Clinical Center for Infectious Diseases, Saint-Petersburg; North-Western State Medical University named after I.I. Mechnikov, Saint-Petersburg
Russian Federation
Russian Federation
M. K. Behtereva
Pediatric Research and Clinical Center for Infectious Diseases, Saint-Petersburg; Saint Petersburg State Pediatric Medical University, Saint-Petersburg
Russian Federation
Russian Federation
Yu. V. Lobzin
Pediatric Research and Clinical Center for Infectious Diseases, Saint-Petersburg; North-Western State Medical University named after I.I. Mechnikov, Saint-Petersburg; Military Medical Academy named after S.M. Kirov, Saint-Petersburg
Russian Federation
Russian Federation
References
1. Child Health Epidemiology Reference Group of the World Health Organization and UNICEF Global causes of diarrheal disease mortality in children younger 5 years of age: a systematic review / C.F. Lanata [et al.] // PLoSOne. – 2013. – Vol. 8, № 9. – P. e72788.
2. Ermolenko, K.D. Virusnye gastroehnterity u detej: sovremennye predstavleniya ob ehpidemiologii i profilaktike / K.D. Ermolenko, YU.V. Lobzin, N.V. Gonchar // ZHurn. infektologii. – 2015. – T. 7, № 3. – C. 22-32.
3. Gorelov, A.V. Rotavirusnaya infekciya u detej / A.V. Gorelov, D.V. Usenko // Vopr. sovrem. pediatrii. – 2008. – T. 7, № 6. – S. 78-84.
4. Denisyuk, N.B. EHtiologicheskaya struktura i nekotorye klinicheskie osobennosti kishechnyh infekcij u detej, gospitalizirovannyh v infekcionnyj stacionar g. Orenburga / N.B. Denisyuk, YU.D. Kagan // Med. al’manah. – 2013. – T. 30, № 6. – S. 143-146.
5. Mayanskij, N.A. Rotavirusnaya infekciya: ehpidemiologiya, patologiya, vakcinoprofilaktika / N.A. Mayanskij, A.N. Mayanskij // Vestn. Ros. akademii med. nauk. – 2015. – № 1. – S. 47-54.
6. Ruzhencova T. A., Ploskireva A. A., Gorelov A. V. Oslozhneniya rotavirusnoj infekcii u detej //Pediatriya named after GN Speransky. – 2016. – T. 95. – №. 2.
7. Bel’mer, S.V. Funkcional’nye i strukturnye narusheniya organov pishchevareniya u detej: v poiskah granic i kriteriev / S.V. Bel’mer // Ros. vestn. perinatologii i pediatrii. – 2013. – T. 58, № 1. – C. 4-7.
8. Aslan A. et al. Comparison of Vesikari and Clark scales regarding the definition of severe rotavirus gastroenteritis in children //Infectious Diseases. – 2015. – T. 47. – №. 5. – S. 332-337.
9. Schnadower D. et al. Validation of the modified Vesikari score in children with gastroenteritis in 5 US emergency departments //Journal of pediatric gastroenterology and nutrition. – 2013. – T. 57. – №. 4. – S. 514.
10. Viera A. J. et al. Understanding interobserver agreement: the kappa statistic //Fam Med. – 2005. – T. 37. – №. 5. – S. 360-363.
11. Drossman, D.A. Functional Gastrointestinal Disorders: History, Pathophysiology, Clinical Features and Rome IV / D.A. Drossman // Gastroenterology. – 2016. – Vol. 150, № 6. – P. 1262-1279.
12. Sowmyanarayanan T. V. et al. Severity of rotavirus gastroenteritis in Indian children requiring hospitalization //Vaccine. – 2012. – T. 30. – S. A167-A172.
13. Ermolenko K. D. i dr. Rol’ ostryh kishechnyh infekcij virusnoj ehtiologii v formirovanii funkcional’noj patologii zheludochno-kishechnogo trakta u detej //Farmateka. – 2016. – №. 1. – S. 55-61.
14. Givon-Lavi N., Greenberg D., Dagan R. Comparison between two severity scoring scales commonly used in the evaluation of rotavirus gastroenteritis in children //Vaccine. – 2008. – T. 26. – №. 46. – S. 5798-5801.
Review
For citations:
Ermolenko K.D., Gonchar N.V., Behtereva M.K., Lobzin Yu.V. Comparison of vezikari and clark scale for determination of of viral intestinal infections sevitity and predicting their outputs in children. Journal Infectology. 2018;10(4):64-71. (In Russ.) https://doi.org/10.22625/2072-6732-2018-10-4-64-71
Views:
1316
.png)
.png)
Email this article 