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Elimination of hcv-infection: a history with continuation

https://doi.org/10.22625/2072-6732-2018-10-4-6-13

Abstract

Chronic hepatitis C remains one of the most important socially significant infections for world health. The use of modern highly effective drugs with direct antiviral action allows to achieve a sustained virological response in patients. At the same time, in a significant number of cases after elimination of HCV infection, the progression of fibrosis continues with the development of its terminal stages and an unfavorable outcome for patients. The article focuses on comorbid pathology, which is a leading factor in this process in patients with chronic hepatitis C who have achieved a sustained virological response and presenting a serious challenge to modern hepatology.

About the Authors

K. V. Zhdanov
Military Medical Academy named after S.M. Kirov, Saint-Petersburg
Russian Federation


K. V. Kozlov
Military Medical Academy named after S.M. Kirov, Saint-Petersburg
Russian Federation


V. S. Sukachev
Military Medical Academy named after S.M. Kirov, Saint-Petersburg
Russian Federation


S. M. Zaharenko
Military Medical Academy named after S.M. Kirov, Saint-Petersburg
Russian Federation


S. S. Karyakin
Military Medical Academy named after S.M. Kirov, Saint-Petersburg
Russian Federation


A. V. Saulevich
Military Medical Academy named after S.M. Kirov, Saint-Petersburg
Russian Federation


D. Yu. Lobzin
Military Medical Academy named after S.M. Kirov, Saint-Petersburg
Russian Federation


M. V. Yaryemenko
Military Medical Academy named after S.M. Kirov, Saint-Petersburg
Russian Federation


K. S. Ivanov
Military Medical Academy named after S.M. Kirov, Saint-Petersburg
Russian Federation


Yu. I. Lyashenko
Military Medical Academy named after S.M. Kirov, Saint-Petersburg
Russian Federation


V. E. Karev
Pediatric Research and Clinical Center for Infectious Diseases, Saint-Petersburg
Russian Federation


Yu. F. Zaharkiv
Military Medical Academy named after S.M. Kirov, Saint-Petersburg
Russian Federation


Yu. I. Bulan’kov
Military Medical Academy named after S.M. Kirov, Saint-Petersburg
Russian Federation


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Review

For citations:


Zhdanov K.V., Kozlov K.V., Sukachev V.S., Zaharenko S.M., Karyakin S.S., Saulevich A.V., Lobzin D.Yu., Yaryemenko M.V., Ivanov K.S., Lyashenko Yu.I., Karev V.E., Zaharkiv Yu.F., Bulan’kov Yu.I. Elimination of hcv-infection: a history with continuation. Journal Infectology. 2018;10(4):6-13. (In Russ.) https://doi.org/10.22625/2072-6732-2018-10-4-6-13

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ISSN 2072-6732 (Print)