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ESOPHAGEAL ACTINOMYCOSIS IN RECIPIENT AFTER HEART TRANSPLANTATION

https://doi.org/10.22625/2072-6732-2018-10-3-147-150

Abstract

In this article, we reported a clinical case of late posttransplant complication – esophageal actinomycosis in 58-yr-old woman 8 months after heart transplantation. Recipient had presented with a complaint of dyspeptic phenomena. Patient’s examination did not show any features. Blood results were fine but tacrolimus concentration was increased (24 ng/ml). Esophagogastroduodenoscopy identified signs of esophageal candidiasis, biopsy was taken. Histological examination revealed esophageal actinomycosis. According to other investigations we did not find any signs of antinomycosis in other organs. Taking into account the results of obtained research, there was no evidence of deep tissue invasion and no indications for surgical treatment, conservative management was chosen. Three months of antibacterial treatment (Doxycycline) was effective. Considering long-term management of this complication in out-patient department it is important to accomplish strictly the protocol of posttransplant follow-up, the same as it allows to diagnose in time. Conservative management of esophageal actinomycosis diagnosed on early stage can be effective.

About the Authors

M. A. Simonenko
National Medical Research Centre named after V.A. Almazov
Russian Federation
Saint-Petersburg


P. A. Fedotov
National Medical Research Centre named after V.A. Almazov
Russian Federation
Saint-Petersburg


K. I. Monosova
National Medical Research Centre named after V.A. Almazov
Russian Federation
Saint-Petersburg


Yu. V. Sazonova
National Medical Research Centre named after V.A. Almazov
Russian Federation
Saint-Petersburg


L. B. Mitrofanova
National Medical Research Centre named after V.A. Almazov
Russian Federation
Saint-Petersburg


M. A. Karpenko
National Medical Research Centre named after V.A. Almazov
Russian Federation
Saint-Petersburg


References

1. On behalf of Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseses – Chapter 2-12-1. Anaerobic infections (individual fields): actinomycosis. Japanese Infectious Chemotherapy (2011) 17 (Supplement 1): 119- 120. DOI: 10.1007/s10156-010-0154-5

2. Valour F, Sénéchal A, Dupieux C, Karsenty J, Lustig S, Breton P, Gleizal A, Boussel L, Laurent F, Braun E, Chidiac C, Ader F, Ferry T – Actinomycosis: etiology, clinical features, diagnosis, treatment, and management. Dove Press Journal: Infection and Drug Resistance, 5 July 2014, 183-197. DOI: 10.2147/IDR.S39601

3. Klimko N.N. – Mikozy: diagnostika i lechenie. Rukovodstvo dlya vrachey. Izdaniye tretye, dopolnennoye i pererabotannoye. Moskva 2017

4. T. Yagi, H. Fujino, M. Hirai, T. Inoue, M. Sako, H. Teshima, S. Fuji and M. Hino – Esophageal actinomycosis after allogenic peripheral blood stem cell transplantation for extranodal natural killer/T cell lymphoma, nasal type. Bone Marrow Transplantation (2003) 32, 451-453. DOI: 10.1038/sj.bmt.1704161

5. Rodney D. Welling, Diana M. Cardona, William M. Thompson – Esophageal Actinomycosis: A Case Report and Review of Radiographic Findigs. Radiology Case, 2009; 3(12): 44-48. DOI: 10.3941/jrcr.v3i12.297

6. Ashoni K. Arora, Jill Nord, O. Olofinlade and Bruce Javors – Esophageal Actinomycosis: A Case Report and Review of the Literature. Dysphagia, 18:27-31 (2003). DOI: 10.1007/s00455-002-0080-5


Review

For citations:


Simonenko M.A., Fedotov P.A., Monosova K.I., Sazonova Yu.V., Mitrofanova L.B., Karpenko M.A. ESOPHAGEAL ACTINOMYCOSIS IN RECIPIENT AFTER HEART TRANSPLANTATION. Journal Infectology. 2018;10(3):147-150. (In Russ.) https://doi.org/10.22625/2072-6732-2018-10-3-147-150

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ISSN 2072-6732 (Print)