A TYPICAL PATIENT WITH HIV TODAY: COMPREHENSIVE CHARACTERIZATION AND ANTIRETROVIRAL TREATMENT OPTIONS (BASED ON DATA OF THE ST. PETERSBURG AIDS CENTER)
https://doi.org/10.22625/2072-6732-2018-10-1-62-69
Abstract
The objective of the study was to describe patients with HIV infection, who were diagnosed in 2016 in St Petersburg AIDS Center, including provided antiretroviral therapy (ART).
A retrospective review of 521 patients’ case histories was performed. The case history selection was done by random sampling, in which the only criterion was the year of HIVinfection registration.
The majority of patient were young people (middle age -), socially adapted, with higher or secondary special education (%),acquired HIV by sexual rout (%). 44% of patients had a CD4-lymphocyte count less than 350 cells / mm3, indicating a late detection of HIV and advanced stage of the disease at the moment of HIV registration. 25% of patients with a CD4 counts more than 350 cells / mm3 also had clinical symptoms of HIV-infection and needed ART.
41% of patients with HIV had different concomitant noncommunicable diseases, of which one third (29%) received therapy for these diseases. This situation dictates the need for careful choice of ART regimens taking into account the clinical features of patients, concomitant therapy and drugdrug interactions.
About the Authors
D. A. Gusev
Center for Prevention and Control of AIDS and Infectious Diseases
Russian Federation
Russian Federation
N. V. Sizova
Center for Prevention and Control of AIDS and Infectious Diseases
Russian Federation
Russian Federation
S. O. Mayorova
Center for Prevention and Control of AIDS and Infectious Diseases
Russian Federation
Russian Federation
V. V. Bratkova
Center for Prevention and Control of AIDS and Infectious Diseases
Russian Federation
Russian Federation
A. L. Sotnikova
Center for Prevention and Control of AIDS and Infectious Diseases
Russian Federation
Russian Federation
T. V. Malkova
Center for Prevention and Control of AIDS and Infectious Diseases
Russian Federation
Russian Federation
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Review
For citations:
Gusev D.A., Sizova N.V., Mayorova S.O., Bratkova V.V., Sotnikova A.L., Malkova T.V. A TYPICAL PATIENT WITH HIV TODAY: COMPREHENSIVE CHARACTERIZATION AND ANTIRETROVIRAL TREATMENT OPTIONS (BASED ON DATA OF THE ST. PETERSBURG AIDS CENTER). Journal Infectology. 2018;10(1):62-69. (In Russ.) https://doi.org/10.22625/2072-6732-2018-10-1-62-69
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