Detection of Nonpolio Enteroviruses among children with acute flaccid paralysis from institutions and from migrants’ families

Aim: to study of the frequency of isolation and determination of the spectrum of enterovirus serotypes excreted by children living in the North-Western region of Russia and children arriving in this region from unsafe territories.

Materials and methods: we investigated 832 samples of children with acute flaccid paralysis and 1153 samples of healthy children from institutions and migrants’ families. Isolation and identification of enteroviruses were conducted according to WHO recommendations.

Results: enteroviruses of different serotypes were detected in all categories of children. The percentage of detection of enteroviruses in the samples of children from institutions and from migrants’ families was significantly higher than in those of patients with acute flaccid paralysis. In children living in the North-West of Russia we detected enteroviruses ECHO 6, which were not found in children who arrived in the North-Western region of Russia. Enteroviruses ECHO 30 were revealed in resident children more frequently than in children from migrants’ families. Enteroviruses of serotypes which had not circulated earlier in the North-Western region of Russia were revealed in the samples of children from migrants’ families. They were Coxsackieviruses A 13, 17, 24 and enterovirus 99 (species C), enteroviruses 75 and 120 (species B and A).

Conclusion: the difference in the spectrum of enterovirus serotypes excreted by resident children and children who arrived in the North-Western region of Russia from unsafe territories was shown. The obtained data will enlarge the scope of knowledge about enterovirus circulation among various groups of population during different periods of time on different territories.

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