Modern features of varicella encephalitis in children
https://doi.org/10.22625/2072-6732-2009-1-4-36-43
Abstract
There was conducted a survey among 65 children aged from 1 year to 17 with varicella encephalitis. There was determined predominance of cerebellar forms of the disease, in 93,9%, that is characterized by the development of the light pyramidal disorders on the contrast to the cerebral that is characterized by the development of convulsivecomatose syndrome. It was determined that the disease is distinguished by the rareness of the detected changes on the MRI, 12,3% only. It was detected that the changes of the evoked potentials could be seen among all the patients and are characterized by the predominance demyelinating changes of the brainstem structures when having a cerebellar form and neuronal disorders of the cerebral hemisphere when having a cerebral form. The outcome of the cerebellar form is recovery in 100% of cases, and in cerebral – the development of epilepsy was detected in 50% and death in 25%.
About the Authors
N. V. Scripchenko
Research Institute of Children Infection, Saint-Petersburg
Russian Federation
Russian Federation
G. P. Ivanova
Research Institute of Children Infection, Saint-Petersburg
Russian Federation
Russian Federation
V. N. Komantsev
Research Institute of Children Infection, Saint-Petersburg
Russian Federation
Russian Federation
M. V. Savina
Research Institute of Children Infection, Saint-Petersburg
Russian Federation
Russian Federation
References
1. Белозеров Е.С. Болезни герпесвирусной группы /Е.С. Белозеров, Ю.И. Буланьков. – Элиста.: АПП «Джангар», 2005. – 64 с.
2. Иванова В.В. Инфекционные болезни у детей: учебное пособие / под ред. В.В. Ивановой. – М.: ООО «Медицинское информационное агентство», 2002. – 928 с.
3. Зинченко А.П. Острые нейроинфекции у детей: руководство для врачей / Под ред. А.П. Зинченко. – Л.: Медицина, 1986. – 320 с.
4. Сорокина М.Н. Вирусные энцефалиты и менингиты у детей. / М.Н. Сорокина, Н.В. Скрипченко. – М.: Медицина, 2004. – 416 с.
5. Steiner I, Kennedy P.G., Pachner A.R. The neurotropic herpes viruses: herpes simplex and varicella-zoster // Lancet Neurol – 2007. – Vol. 6 (11). – p. 1015–28.
6. Лещинская Е.В. Острые вирусные энцефалиты у детей / Е.В Лещинская, И.Н. Мартыненко – АМН СССР. – М.: Медицина, 1990. – 250с.
7. Whitley R J. Virus encephalitis / R J. Whitley, D.W. Kimber lin // Pediatrics in Review. – 1999. – Vol. 20 (6). – р. 192– 98.
8. Solomon T., Hart I.J., Beeching N.J. Virus encephalitis: a clinicians guide // Practical Neurology. – 2007. – Vol.7. – p. 288–305.
9. Деконенко Е.П. Летальный исход энцефалита после ветряной оспы у пациента с аутоиммунным заболеванием / Е.П. Деконенко, Л.В. Шишкина // Журн. неврол. и психиат. им. Корсакова. – 2005. – №2. – с.54–59.
10. Nebuloni M. VZV fulminant necrotizing encephalitis with cocomitant EBV – related lymphoma and CMV ventriculitis: report of an AIDS case / M. Nebuloni et al. // J. of NeuroVirology. – 1998. – Vol.4. – p. 457–66.
11. Kleinschmidt-deMasters B. K. The pattern of varicella zoster virus encepha-litis / B. K. Kleinschmidt-deMasters, C. Amplie-Lefond, D.H. Gilden // Hum. Pathol. – 1996. – 27(9). – p. 927–38.
12. Recommendations for the Practice of Clinical Neurophysiology: Guidelines of the International Federation of Clinical Neurophysiology // Gunter Deuschl // Electroenceph. Clin. Neurophysiol. – 1999. – Suppl. 52. – p. 79–90.
13. Arvin A.M. Antiviral therapy for varicella and herpes zoster // Seminars in Pediatric Infectious Diseases. – 2002. – Vol.13 (1).– p. 120–6.
14. Roos K.L. Сеntral nervous infections. Encephalitis //Neurologic Clinics – 1999. – Vol.17 (4). – p. 813–33.
Review
For citations:
Scripchenko N.V., Ivanova G.P., Komantsev V.N., Savina M.V. Modern features of varicella encephalitis in children. Journal Infectology. 2009;1(4):36-43. (In Russ.) https://doi.org/10.22625/2072-6732-2009-1-4-36-43
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