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Problems and opportunities for complex treatment of ARVI and other viral infections in children in outpatient practice. Assessing the value of antiviral and local therapy (Resolution of the interdisciplinary Council of Experts)

https://doi.org/10.22625/2072-6732-2025-17-4-181-190

Abstract

In September 2025, a meeting of experts was convened to discuss the problems of modern viral diseases, which are widespread and economically significant. Pathogens capable of causing respiratory tract damage belong to various taxonomic groups and manifest not only with the primary syndrome (respiratory inflammatory syndrome) but also with other diverse lesions of human systems and organs. The council was held in an interdisciplinary format and featured leading experts in pediatrics, infectious diseases, allergology, immunology, dermatology, and pharmacology. Given the significance of viral infections in children and adolescents, several key issues related to improving medical care for this category of patients were discussed. The purpose of the Expert Council was to systematize the available data on the treatment of viral infections affecting the respiratory tract and to exchange clinical experience in the management of pediatric patients (antiviral and immunomodulatory). The use of the drug inosine pranobex by the council members for various viral diseases and the relief of syndromes caused by the lymphoproliferative capabilities of viruses has made it possible to shorten the duration of the disease, its chronicity, reduce the need for antibiotic therapy and the development of complications. Among the effective medications with antiviral and immunostimulatory activity, inosine pranobex is a popular choice. Its active ingredient is inosine pranobex. Its pharmacotherapeutic group is immunostimulant. Its primary pharmacological actions are immunostimulatory and antiviral. Its mechanism of action is primarily the suppression of viral DNA and RNA replication.
Respiratory viral infections remain a significant public health threat, especially to pediatric patients, requiring optimized diagnostic, treatment, and prevention efforts. Prescribing inosine pranobex reduces the recurrence rate of respiratory infections, herpesvirus infections, and other viral diseases, shortens the intensity and duration of acute respiratory viral infections, and improves overall patient well-being.

About the Authors

M. S. Savenkova
Russian National Research Medical University named after N.I. Pirogov
Russian Federation

Moscow



E. V. Esaulenko
Saint-Petersburg State Pediatric Medical University
Russian Federation

Saint-Petersburg



V. A. Petrov
Medical Radiological Research Centre named after A.F. Tsyb – Branch of National Research Medical Centre of Radiology
Russian Federation

Obninsk



N. B. Migacheva
Samara State Medical University
Russian Federation

Samara



N. A. Abramova
Сlinic № 2. «Gazprom Branch Clinical and Diagnostic Centre»
Russian Federation

Moscow



Yа. A. Bogvilene
Krasnoyarsk State Medical University named after Professor V.F. Voyno-Yasenetsky
Russian Federation

Krasnoyarsk



S. V. Khaliullina
Kazan State Medical University
Russian Federation

Kazan



R. A. Ushakova
Urals State Medical University
Russian Federation

Ekaterinburg



G. M. Filippova
Regional Clinical Emergency Hospital № 2
Russian Federation

Barnaul



E. V. Dudnikova
Rostov State Medical University
Russian Federation

Rostov-on-Don



A. P. Ivanova
Kursk State Medical University
Russian Federation

Kursk



O. R. Varnikova
Ivanovo State Medical University
Russian Federation

Ivanovo



N. S. Tataurshchikova
Russian University of People`s Frienndship named after Patrice Lumumba
Russian Federation

Moscow



V. G. Yankova
First Moscow State Medical University named after I.M. Sechenov
Russian Federation

Moscow



K. E. Novak
Saint-Petersburg State Pediatric Medical University
Russian Federation

Saint-Petersburg



A. D. Ibrokhimova
Saint-Petersburg State Pediatric Medical University
Russian Federation

Saint-Petersburg



M. G. Pozdnyakova
Saint-Petersburg State Pediatric Medical University
Russian Federation

Saint-Petersburg



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Savenkova M.S., Esaulenko E.V., Petrov V.A., Migacheva N.B., Abramova N.A., Bogvilene Y.A., Khaliullina S.V., Ushakova R.A., Filippova G.M., Dudnikova E.V., Ivanova A.P., Varnikova O.R., Tataurshchikova N.S., Yankova V.G., Novak K.E., Ibrokhimova A.D., Pozdnyakova M.G. Problems and opportunities for complex treatment of ARVI and other viral infections in children in outpatient practice. Assessing the value of antiviral and local therapy (Resolution of the interdisciplinary Council of Experts). Journal Infectology. 2025;17(4):181-190. (In Russ.) https://doi.org/10.22625/2072-6732-2025-17-4-181-190

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