Atraumatic splenic rupture with acute Varicella-Zoster infection (chickenpox)
https://doi.org/10.22625/2072-6732-2025-17-1-120-124
Abstract
Chickenpox, despite of introduction of vaccination, remains a common disease, mainly among children. In most cases, chickenpox is a self-limiting disease without the development of life-threatening conditions. The case of atraumatic splenic rupture associated with chickenpox is a too rare and we described seventh case over the past 55 years. The man was hospitalized in the infectious diseases hospital with a vesicular rash, abdominal pain and repeated vomiting with a referral diagnosis of “acute pancreatitis, chickenpox”. The diagnosis of chickenpox was confirmed (family contact, typical rash and IgM-VZV). Splenic rupture was described with computed tomography with a contrasting agent. Splenectomy performed in first day of hospitalization. Symptoms resolved against the background of antiviral therapy. There were no surgical complications.
About the Authors
M. A. Sayfullin
Russian National Research Medical University named after N.I. Pirogov
Russian Federation
Competing Interests:
Russian Federation
Moscow
Competing Interests:
None
E. S. Makhinova
Russian National Research Medical University named after N.I. Pirogov
Russian Federation
Competing Interests:
Russian Federation
Moscow
Competing Interests:
None
N. N. Zvereva
Russian National Research Medical University named after N.I. Pirogov
Russian Federation
Competing Interests:
Russian Federation
Moscow
Competing Interests:
None
V. A. Morozov
Infectious Diseases Clinical Hospital № 1
Russian Federation
Competing Interests:
Russian Federation
Moscow
Competing Interests:
None
E. A. Volobueva
Infectious Diseases Clinical Hospital № 1
Russian Federation
Competing Interests:
Russian Federation
Moscow
Competing Interests:
None
A. A. Bogomolova
Infectious Diseases Clinical Hospital № 1
Russian Federation
Competing Interests:
Russian Federation
Moscow
Competing Interests:
None
I. N. Tyurin
Russian National Research Medical University named after N.I. Pirogov; Infectious Diseases Clinical Hospital № 1
Russian Federation
Competing Interests:
Russian Federation
Moscow
Competing Interests:
None
References
1. Eichner E.R, Whitfield C.L. Splenomegaly. An algorithmic approach to diagnosis. JAMA. 1981 Dec 18. 246 (24):2858-61 Онлайн доступ https://jamanetwork.com/journals/jama/article-abstract/365758 от 28.11.2024
2. Stockinger Z.T. Infectious mononucleosis presenting as spontaneous splenic rupture without other symptoms. Mil Med. 2003 Sep;168(9):722-4. Онлайн доступ https://academic.oup.com/milmed/article-abstract/168/9/722/4820260 от 28.11.2024
3. Renzulli P., Hostettler A., Schoepfer A.M., Gloor B., Candinas D. Systematic review of atraumatic splenic rupture. Br J Surg. 2009 Oct;96(10):1114-21. doi: 10.1002/bjs.6737.
4. Zryachkin N.I., Buchkova T.N., Chebotareva G.I. Complications of chickenpox (literature review). Journal Infectology. 2017;9(3):117-128. (In Russ.) https://doi.org/10.22625/2072-6732-2017-9-3-117-128
5. Uthayakumar A., Harrington D. Spontaneous splenic rupture complicating primary varicella zoster infection: a case report. BMC Res Notes. 2018 May 22;11(1):334. https://doi.org/10.1186/s13104-018-3430-6
6. Sykes M.C., Azhar B., John L., Bokhari S. Open splenectomy for Varicella zoster induced spontaneous splenic rupture. Int J Surg Case Rep. 2018; 42:237-241. https://doi.org/10.1016/j.ijscr.2017.11.070.
7. Clifton L.J., Dhaliwal K.S., Saif D., Mullerat P. Varicella zoster virus infection is an unusual cause of splenic rupture. BMJ Case Rep. 2015 Aug 13;2015:bcr2015210909. doi: 10.1136/bcr-2015-210909.
8. Tapp E. Ruptured spleen associated with chickenpox. BMJ. 1969;1(5644):617–8. https://doi.org/10.1136/bmj.1.5644.617
9. Ul Yaqin H. Spontaneous rupture of the spleen in the prodromal period of chickenpox. Postgrad Med J. 1969;45(519):51–3. https://doi.org/10.1136/pgmj.45.519.51
10. Vial I., Hamidou M., Coste-Burel M., Baron D. Abdominal pain in varicella: an unusual case of spontaneous splenic rupture. Eur J Emerg Med. 2004; 11:176–7. https://doi.org/10.1097/01.mej.0000104026.33339.d5
11. Harris R.A., Boland S. L. Varicella zoster associated with spontaneous splenic rupture. Aust N Z J Surg. 1998;68(2):162–3. https://doi.org/10.1111/j.1445-2197.1998.tb04733.x
12. Laing K.J., Ouwendijk W.J.D., Koelle D.M., Verjans G.M. Immunobiology of Varicella-Zoster Virus Infection. J Infect Dis. 2018 Sep 22;218 (suppl_2):S68-S74. doi: 10.1093/infdis/jiy403.
Review
For citations:
Sayfullin M.A., Makhinova E.S., Zvereva N.N., Morozov V.A., Volobueva E.A., Bogomolova A.A., Tyurin I.N. Atraumatic splenic rupture with acute Varicella-Zoster infection (chickenpox). Journal Infectology. 2025;17(1):120-124. (In Russ.) https://doi.org/10.22625/2072-6732-2025-17-1-120-124
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