Prolonged course of novel coronavirus infection COVID-19 with the formation of pulmonary fibrosis in an HIV-infected patient
https://doi.org/10.22625/2072-6732-2024-16-1-87-93
Abstract
A description of a clinical case of a severe, protracted course of coronavirus infection (COVID-19) in a patient with advanced stage HIV infection, characterized by prolonged release of the SARS-CoV-2 virus and the formation of pulmonary fibrosis against the background of an active viral infection, is presented. COVID-19 infection occurred in an immunosuppressed patient without ART. During the period of inpatient treatment, a comprehensive examination was carried out to exclude HIV-associated lung lesions; no evidence of viral, fungal, or bacterial pathology was obtained; mycobacterial infections were also excluded. Despite two courses of antiviral therapy, the use of anti-Covid plasma and complex pathogenetic therapy, persistence of SARS-CoV-2 replication was observed for eight months, with a steady progression of the disease, ending in death.
About the Authors
M. A. Savchenko
Clinical Infectious Disease Hospital named after S.P. Botkin
Russian Federation
Russian Federation
Saint-Petersburg
V. B. Musatov
Clinical Infectious Disease Hospital named after S.P. Botkin;
Saint-Petersburg State University
Russian Federation
Russian Federation
Saint-Petersburg
D. A. Gusev
Clinical Infectious Disease Hospital named after S.P. Botkin;
National Medical Research Centre named after V.A. Almazov
Russian Federation
Russian Federation
Saint-Petersburg
V. A. Cinzerling
Clinical Infectious Disease Hospital named after S.P. Botkin;
National Medical Research Centre named after V.A. Almazov
Russian Federation
Russian Federation
Saint-Petersburg
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Review
For citations:
Savchenko M.A., Musatov V.B., Gusev D.A., Cinzerling V.A. Prolonged course of novel coronavirus infection COVID-19 with the formation of pulmonary fibrosis in an HIV-infected patient. Journal Infectology. 2024;16(1):87-93. (In Russ.) https://doi.org/10.22625/2072-6732-2024-16-1-87-93
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