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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">jofin</journal-id><journal-title-group><journal-title xml:lang="ru">Журнал инфектологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal Infectology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-6732</issn><publisher><publisher-name>IPO “АIDSSPbR"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22625/2072-6732-2019-11-3-131-135</article-id><article-id custom-type="elpub" pub-id-type="custom">jofin-942</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Клинический случай</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Clinical Case</subject></subj-group></article-categories><title-group><article-title>ПЕРВЫЙ СЛУЧАЙ УСПЕШНОГО ЛЕЧЕНИЯ АКТИНОМИКОЗА КОЛЕННОГО СУСТАВА У РЕБЕНКА</article-title><trans-title-group xml:lang="en"><trans-title>First case of the succesful treatment of actinomicosis of the knee in a child</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Козлова</surname><given-names>О. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Kozlova</surname><given-names>O. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Козлова Ольга Петровна – ассистент кафедры клинический микологии, аллергологии и иммунологии</p><p>тел.: +7-906-252-09-70</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"/><email xlink:type="simple">olgakozlova07@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Исаева</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Isaeva</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Исаева Нармина – студентка 6-го курса лечебного факультета</p><p>тел.: +7-931-369-37-31</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Saint-Petersburg</p></bio><email xlink:type="simple">issa.narmina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Авдеенко</surname><given-names>Ю. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Avdeenko</surname><given-names>Yu. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Авдеенко Юрий Леонидович – старший научный сотрудник НИЛ патоморфологии и цитологии Научно-исследовательского института медицинской микологии им. П.Н. Кашкина, к.м.н.</p><p>тел.: +7-911-113-05-80</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Saint-Petersburg</p></bio><email xlink:type="simple">yurii.Avdeenko@szgmu.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Климко</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Klimko</surname><given-names>N. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Климко Николай Николаевич – заведующий кафедрой клинической микологии, аллергологии и иммунологии, д.м.н., профессор</p><p>тел.: 8(812)303-51-46</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Saint-Petersburg</p></bio><email xlink:type="simple">n_klimko@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Северо-Западный государственный медицинский университет им. И.И. Мечникова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>North-Western State Medical University named after I.I. Metchnikov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>09</day><month>10</month><year>2019</year></pub-date><volume>11</volume><issue>3</issue><fpage>131</fpage><lpage>135</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Козлова О.П., Исаева Н.В., Авдеенко Ю.Л., Климко Н.Н., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Козлова О.П., Исаева Н.В., Авдеенко Ю.Л., Климко Н.Н.</copyright-holder><copyright-holder xml:lang="en">Kozlova O.P., Isaeva N.V., Avdeenko Y.L., Klimko N.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.niidi.ru/jofin/article/view/942">https://journal.niidi.ru/jofin/article/view/942</self-uri><abstract><p>Цель: актиномикоз у детей изучен недостаточно, количество публикаций ограничено. Актиномикоз коленного сустава встречается очень редко, заболевание имитирует туберкулез или злокачественные новообразования, что может привести к поздней диагностике и неадекватному лечению. Материалы и методы: мы сообщаем о первом случае успешного лечения актиномикоза коленного сустава у 8-летней девочки. Диагноз был установлен на основании гистологического исследования послеоперационного материала. Результаты: хирургическая резекция инфицированной ткани и антибактериальная терапия в течение 4,5 месяцев привели к положительному результату. В научной литературе подобных клинических примеров не найдено. Заключение: впервые представлен случай успешного лечения актиномикоза коленного сустава у ребенка.</p></abstract><trans-abstract xml:lang="en"><p>Objectives. Actinomycosis in children has not been studied enough, the number of publications is limited. Actinomycosis of the knee joint is very rare, the disease mimics tuberculosis or malignant neoplasms, which can lead to late diagnosis and inadequate treatment. Materials and methods. We report on the first case of an 8-year-girl with actinomycosis knee. Diagnosis is based on histological examination. Results. Surgical resection of infected tissue and longterm antibiotic therapy for 4.5 months was effective in the treatment of pediatric patient with knee actinomycosis. In the scientific literature no such clinical case was found. Сonclusion. Case of successful treatment of pediatric patient with knee actinomycosis is presented for the first time.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>актиномикоз</kwd><kwd>Actinomyces</kwd><kwd>пенициллины</kwd></kwd-group><kwd-group xml:lang="en"><kwd>actinomycosis</kwd><kwd>Actinomyces</kwd><kwd>penicillins</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Moniruddin A.B., Begum H., Nahar K. Actinomycosis: An Update .Medicine today. 2010; 22(1):43-47</mixed-citation><mixed-citation xml:lang="en">Moniruddin A.B., Begum H., Nahar K. Actinomycosis: An Update .Medicine today. 2010; 22(1):43-47</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Russo T.A., Mandell G.L., Bennet J.E., Dolin R. Agents of actinomycosis. Principles and Practice of Infectious Diseases. 6th ed. Churchill Livingstone; New York. 2005;p.2925–2932</mixed-citation><mixed-citation xml:lang="en">Russo T.A., Mandell G.L., Bennet J.E., Dolin R. Agents of actinomycosis. Principles and Practice of Infectious Diseases. 6th ed. Churchill Livingstone; New York. 2005;p.2925–2932</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Valour F., Sénéchal A., Dupieux C., Karsenty J., Lustig S., Breton P., Gleizal A., Boussel L., Laurent F., Braun E., Chidiac C., Ader F., Ferry T. Actinomycosis: etiology, clinical features, diagnosis, treatment, and management. Infection Drug Resist. 2014; 7:183–197</mixed-citation><mixed-citation xml:lang="en">Valour F., Sénéchal A., Dupieux C., Karsenty J., Lustig S., Breton P., Gleizal A., Boussel L., Laurent F., Braun E., Chidiac C., Ader F., Ferry T. Actinomycosis: etiology, clinical features, diagnosis, treatment, and management. Infection Drug Resist. 2014; 7:183–197</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Bonnefond S., Catroux M., Melenotte C., Karkowski L., Rolland L., Trouillier S., Raffray L. Clinical features of actinomycosis: A retrospective, multicenter study of 28 cases of miscellaneous presentations. Medicine (Baltimore). 2016; 95(24):e3923. doi: 10.1097/MD.0000000000003923</mixed-citation><mixed-citation xml:lang="en">Bonnefond S., Catroux M., Melenotte C., Karkowski L., Rolland L., Trouillier S., Raffray L. Clinical features of actinomycosis: A retrospective, multicenter study of 28 cases of miscellaneous presentations. Medicine (Baltimore). 2016; 95(24):e3923. doi: 10.1097/MD.0000000000003923</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Ruhe J., Holding K., Mushatt D. Infected total knee arthroplasty due to Actinomyces naeslundii. Scand J Infect Dis. 2001;33:230–231</mixed-citation><mixed-citation xml:lang="en">Ruhe J., Holding K., Mushatt D. Infected total knee arthroplasty due to Actinomyces naeslundii. Scand J Infect Dis. 2001;33:230–231</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Dom K., Pittevils T. Synovial actinomycosis of the hip: case report and review. Acta Orthopaedica Belgica. 1999;65:242–244</mixed-citation><mixed-citation xml:lang="en">Dom K., Pittevils T. Synovial actinomycosis of the hip: case report and review. Acta Orthopaedica Belgica. 1999;65:242–244</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Nicholson P., Kiely P., Street J., Mahalingum K. Septic arthritis due to Actinomyces pyogenes. Injury. 1998;29:640–642</mixed-citation><mixed-citation xml:lang="en">Nicholson P., Kiely P., Street J., Mahalingum K. Septic arthritis due to Actinomyces pyogenes. Injury. 1998;29:640–642</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Bose R., Karjoo R., Makarem E.H. Synovial actinomycosis of the knee: a case report. British Journal of Surgery. 1979;66:437</mixed-citation><mixed-citation xml:lang="en">Bose R., Karjoo R., Makarem E.H. Synovial actinomycosis of the knee: a case report. British Journal of Surgery. 1979;66:437</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Wüst J., Steiger U., Vuong H., Zbinden R. Infection of a Hip Prosthesis by Actinomyces naeslundii. Journal of Clinical Microbiology. 2000;38(2):929–930</mixed-citation><mixed-citation xml:lang="en">Wüst J., Steiger U., Vuong H., Zbinden R. Infection of a Hip Prosthesis by Actinomyces naeslundii. Journal of Clinical Microbiology. 2000;38(2):929–930</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Petrini B., Welin-Berger T. Late infection with Actinomyces israelii after total hip replacement. Scandinavian Journal of Infectious Diseases.1978; 10(4):313-314</mixed-citation><mixed-citation xml:lang="en">Petrini B., Welin-Berger T. Late infection with Actinomyces israelii after total hip replacement. Scandinavian Journal of Infectious Diseases.1978; 10(4):313-314</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Strazzeri J.C., Anzel S. Infected total hip arthroplasty due to Actinomyces israelii after dental extraction. A case report. Clinical Orthopaedics and Related Research.1986;2106:128-131</mixed-citation><mixed-citation xml:lang="en">Strazzeri J.C., Anzel S. Infected total hip arthroplasty due to Actinomyces israelii after dental extraction. A case report. Clinical Orthopaedics and Related Research.1986;2106:128-131</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Dubourg G., Delord M., Gouriet F., Fournier P., Drancourt M. Actinomyces gerencseriae hip prosthesis infection: a case report. Journal of Medical Case Reports.2015; 9:223. doi: 10.1186/s13256-015-0704-7</mixed-citation><mixed-citation xml:lang="en">Dubourg G., Delord M., Gouriet F., Fournier P., Drancourt M. Actinomyces gerencseriae hip prosthesis infection: a case report. Journal of Medical Case Reports.2015; 9:223. doi: 10.1186/s13256-015-0704-7</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Pierre I., Zarrouk V., Noussair L. Invasive actinomycosis: surrogate marker of a poor prognosis in immunocompromised patients. International Journal of Infectious Diseases. 2014;29:74-79</mixed-citation><mixed-citation xml:lang="en">Pierre I., Zarrouk V., Noussair L. Invasive actinomycosis: surrogate marker of a poor prognosis in immunocompromised patients. International Journal of Infectious Diseases. 2014;29:74-79</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Климко, Н.Н. Микозы: Диагностика и лечение / Н.Н. Климко. –Руководство для врачей. 3-е изд. Перераб. И доп. – М.: Фармтек. – 2017. – 272 с.</mixed-citation><mixed-citation xml:lang="en">Klimko, N.N. Mycoses: Diagnosis and treatment / N.N. Klimko. –Manual for doctors. 3rd ed. Recycling And add. - M.: Farmtek. - 2017. - 272 p.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Wong V.K., Turmezei T.D., Weston V.C. Actinomycosis. British Medical Journal. 2011;oct.:343. doi: https://doi.org/10.1136/bmj.d6099</mixed-citation><mixed-citation xml:lang="en">Wong V.K., Turmezei T.D., Weston V.C. Actinomycosis. British Medical Journal. 2011;oct.:343. doi: https://doi.org/10.1136/bmj.d6099</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Sung H.Y., Lee I.S., Kim S.I., Jung S.E., Kim S.W., Kim S.Y., Chung M.K., Kim W.C., Oh S.T., Kang W.K. Clinical features of abdominal actinomycosis: a 15-year experience of a single institute. Journal of Korean Medical Science. 2011;26(7):932-937. doi:10.3346/jkms.2011.26.7.932</mixed-citation><mixed-citation xml:lang="en">Sung H.Y., Lee I.S., Kim S.I., Jung S.E., Kim S.W., Kim S.Y., Chung M.K., Kim W.C., Oh S.T., Kang W.K. Clinical features of abdominal actinomycosis: a 15-year experience of a single institute. Journal of Korean Medical Science. 2011;26(7):932-937. doi:10.3346/jkms.2011.26.7.932</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Козлова, О.П. Случай успешного лечения торакального актиномикоза / О.П. Козлова [и др.] // Проблемы медицинской микологии. – 2013. – Т. 15, № 2. – С. 35–40.</mixed-citation><mixed-citation xml:lang="en">Kozlova, O.P. A case of successful treatment of thoracic actinomycosis / OP Kozlova, R.M. Chernopyatov, V.S. Mitrofanov, Yu.V. Borzova, S.M. Nuraliev, A.K. Mirzabalayeva, N.N. Klimko // Problems of medical mycology. - 2013. - T.15, №2. - p. 35-40</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
