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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">jofin</journal-id><journal-title-group><journal-title xml:lang="ru">Журнал инфектологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal Infectology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-6732</issn><publisher><publisher-name>IPO “АIDSSPbR"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22625/2072-6732-2012-4-2-5-14</article-id><article-id custom-type="elpub" pub-id-type="custom">jofin-92</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Обзоры</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Review</subject></subj-group></article-categories><title-group><article-title>СОВРЕМЕННЫЕ ПРЕДСТАВЛЕНИЯ О ПАТОГЕНЕЗЕ ИКСОДОВЫХ КЛЕЩЕВЫХ БОРРЕЛИОЗОВ</article-title><trans-title-group xml:lang="en"><trans-title>Current knowledge of Lyme disease’s pathogenesis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Скрипченко</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Skripchenko</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>заместитель директора по научной работе НИИ детских инфекций ФМБА России, д.м.н., профессор; тел. (812)234-10-38</p></bio><email xlink:type="simple">rmtc@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Балинова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Balinova</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>очный аспирант отдела нейроинфекций и органической патологии нервной системы НИИ детских инфекций ФМБА России; тел.: (812)234-19-01</p></bio><email xlink:type="simple">balinovaalexandra1@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-исследовательский институт детских инфекций ФМБА России, Санкт-Петербург</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute of Children Infections FMBA of Russia, Saint-Petersburg</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>12</day><month>09</month><year>2014</year></pub-date><volume>4</volume><issue>2</issue><fpage>5</fpage><lpage>14</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Скрипченко Н.В., Балинова А.А., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Скрипченко Н.В., Балинова А.А.</copyright-holder><copyright-holder xml:lang="en">Skripchenko N.V., Balinova A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.niidi.ru/jofin/article/view/92">https://journal.niidi.ru/jofin/article/view/92</self-uri><abstract><p>В обзоре представлены современные микробиологические, иммунологические и молекулярно-генетические особенности иксодовых клещевых боррелиозов. Описаны механизмы диссиминации и адаптации боррелий в условиях макроорганизма. Освещена роль B. burgdorferi s.l. в развитии аутоиммунных заболеваний и неходжскинских лимфом.</p></abstract><trans-abstract xml:lang="en"><p>This review present current immunological, microbiological and molecular genetic features of Lyme disease. The mechanisms of borrelia’s dissemination and adaptation in the macroorganism are describe. The role of B. burgdorferi s.l. in the development of autoimmune diseases and non-Hodgkin-lymfomas is describe.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>иксодовые клещевые боррелиозы</kwd><kwd>иммунный ответ</kwd><kwd>ген</kwd><kwd>Borrelia burgdorferi</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Lyme disease</kwd><kwd>immune response</kwd><kwd>gen</kwd><kwd>Borrelia burgdorferi s.l.</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Агафьина, А.С. 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