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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">jofin</journal-id><journal-title-group><journal-title xml:lang="ru">Журнал инфектологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal Infectology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-6732</issn><publisher><publisher-name>IPO “АIDSSPbR"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22625/2072-6732-2018-10-4-139-144</article-id><article-id custom-type="elpub" pub-id-type="custom">jofin-815</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Клинический случай</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Clinical Case</subject></subj-group></article-categories><title-group><article-title>ТРУДНОСТИ ДИАГНОСТИКИ БОКОВОГО АМИОТРОФИЧЕСКОГО СКЛЕРОЗА У ВИЧ-ИНФИЦИРОВАННОГО ПАЦИЕНТА</article-title><trans-title-group xml:lang="en"><trans-title>Difficulties in diagnosing amyotrophic lateral sclerosis in a HIV-Positive Patient</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексеева</surname><given-names>Т. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Alekseeva</surname><given-names>T. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>заведующая кафедрой неврологии и психиатрии института медицинскогообразования и научно-исследовательской лаборатории неврологии научно-исследовательского отдела неврологии и нейрореабилитации,д.м.н.; </p><p>тел.: 8(812)702-37-49 доб. 001745 </p></bio><email xlink:type="simple">atmspb@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Скрипченко</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Skripchenko</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>заместитель директора по научной работе, руководитель центрадемиелинизирующих заболеваний и рассеянного склероза у детей; заведующая кафедрой инфекционных болезней ФП и ДПО, д.м.н., профессор, заслуженный деятель науки РФ; </p><p>тел.: 8(812)234-10-38 </p></bio><email xlink:type="simple">snv@niidi.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лобзин</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lobzin</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>заведующий кафедрой неврологии имени академика С.Н. Давиденкова, д.м.н., профессор; </p><p>тел.: 8(812)303-50-00 доб. 8672 </p></bio><email xlink:type="simple">Sergei.Lobzin@szgmu.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Демешонок</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Demeshonok</surname><given-names>V. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-невролог; </p><p>тел.: 8(812)303-50-00 доб. 8672 </p></bio><email xlink:type="simple">demeshonokvs@gmail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юркина</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Yurkina</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ассистент кафедры неврологии имени академика С.Н. Давиденкова, к.м.н.; </p><p>тел.: 8(812)303-50-00 доб. 8672 </p></bio><email xlink:type="simple">eayurkina@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Назаров</surname><given-names>В. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Nazarov</surname><given-names>V. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>младший научный сотрудник лаборатории диагностики аутоиммунныхзаболеваний научно-методического центра по молекулярной медицине; </p><p>тел.: 8(812)994-53-24 </p></bio><email xlink:type="simple">Nazarov19932@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лапин</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lapin</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>заведующий лабораторией диагностики аутоиммунных заболеванийнаучно-методического центра по молекулярной медицине, к.м.н.; </p><p>тел.: 8(812)994-53-24 </p></bio><email xlink:type="simple">svlapin@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр им. В.А. Алмазова, Санкт-Петербург</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center named after V.A. Almazov, Saint-Petersburg</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Детский научно-клинический центр инфекционных болезней, Санкт-Петербург; Санкт-Петербургский государственный педиатрический медицинский университет, Санкт-Петербург</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pediatric Research and Clinical Center for Infectious Diseases, Saint-Petersburg; Saint-Petersburg State Pediatric Medical University, Saint-Petersburg</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Северо-Западный государственный медицинский университет им. И.И. Мечникова, Санкт-Петербург</institution><country>Россия</country></aff><aff xml:lang="en"><institution>North-Western State Medical University named after I.I. Mechnikov, Saint-Petersburg</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Первый Санкт-Петербургский государственный медицинский университет им. академика И.П. Павлова, Санкт-Петербург</institution><country>Россия</country></aff><aff xml:lang="en"><institution>First Saint-Petersburg State Medical University named after academician I.P. Pavlov, Saint-Petersburg</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2018</year></pub-date><volume>10</volume><issue>4</issue><fpage>139</fpage><lpage>144</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Алексеева Т.М., Скрипченко Н.В., Лобзин С.В., Демешонок В.С., Юркина Е.А., Назаров В.Д., Лапин С.В., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Алексеева Т.М., Скрипченко Н.В., Лобзин С.В., Демешонок В.С., Юркина Е.А., Назаров В.Д., Лапин С.В.</copyright-holder><copyright-holder xml:lang="en">Alekseeva T.M., Skripchenko N.V., Lobzin S.V., Demeshonok V.S., Yurkina E.A., Nazarov V.D., Lapin S.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.niidi.ru/jofin/article/view/815">https://journal.niidi.ru/jofin/article/view/815</self-uri><abstract><p>Описан случай развития бокового амиотрофического склероза (БАС) на фоне ВИЧ-инфекции, подтвержденный данными молекулярно-генетического исследования. Обсуждается сложность дифференциальной диагностики между классическим БАС и БАС-подобным синдромом у ВИЧ-инфицированного пациента.</p></abstract><trans-abstract xml:lang="en"><p>We described a case of amyotrophic lateral sclerosis (ALS) with comorbid HIV infection. The diagnosis was confirmed by genetic tests. The difficulty of the differential diagnosis between amyotrophic lateral sclerosis and HIV-associated ALS syndrome is discussed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>боковой амиотрофический склероз</kwd><kwd>ВИЧ-инфекция</kwd><kwd>ВИЧ-ассоциированный БАС-подобный синдром</kwd><kwd>генетические исследования</kwd><kwd>SOD1</kwd></kwd-group><kwd-group xml:lang="en"><kwd>amyotrophic lateral sclerosis</kwd><kwd>HIV infection</kwd><kwd>HIV-associated ALS syndrome</kwd><kwd>genetic tests</kwd><kwd>SOD1</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Левицкий, Г.Н. Боковой амиотрофический склероз: лечение и теоретические вопросы : монография / Г.Н. Левицкий. – М.: Практическая медицина, 2010. – 568 с.</mixed-citation><mixed-citation xml:lang="en">Levitsky G.N. Amyotrophic lateral sclerosis – treatment and theoretic issues. 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