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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">jofin</journal-id><journal-title-group><journal-title xml:lang="ru">Журнал инфектологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal Infectology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-6732</issn><publisher><publisher-name>IPO “АIDSSPbR"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22625/2072-6732-2018-10-4-134-138</article-id><article-id custom-type="elpub" pub-id-type="custom">jofin-814</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Клинический случай</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Clinical Case</subject></subj-group></article-categories><title-group><article-title>ГАНГРЕНОЗНАЯ ЭКТИМА – ФАТАЛЬНАЯ ФОРМА СИНЕГНОЙНОЙ ИНФЕКЦИИ У РЕБЕНКА ВОСЬМИ МЕСЯЦЕВ</article-title><trans-title-group xml:lang="en"><trans-title>Ecthyma gangrenosum: fatal form of pseudomonas aeruginosa infection in an eight-month-old infant</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рымаренко</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Rymarenko</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>профессор кафедры педиатрии с курсом детских инфекционных болезнейМедицинской академии им. С.И. Георгиевского, д.м.н.; </p><p>тел: +7-978-863-62-33, 8(3652)60-80-22 </p></bio><email xlink:type="simple">natadoc@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бобрышева</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bobrysheva</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доцент кафедры педиатрии с курсом детских инфекционных болезнейМедицинской академии им. С.И. Георгиевского, к.м.н.; </p><p>тел.: +7-978-831-77-07, 8(3652)60-80-22 </p></bio><email xlink:type="simple">alona.radost@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Крюгер</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Krjuger</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доцент кафедры педиатрии с курсом детских инфекционных болезнейМедицинской академии им. С.И. Георгиевского, к.м.н.; </p><p>тел.: +7-978-721-50-65, 8(3652)60-80-22 </p></bio><email xlink:type="simple">elena-krjuger@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Халилов</surname><given-names>Э. Я.</given-names></name><name name-style="western" xml:lang="en"><surname>Halilov</surname><given-names>E. Ya.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ассистент кафедры педиатрии с курсом детских инфекционных болезнейМедицинской академии им. С.И. Георгиевского; </p><p>тел.: +7-978-876-73-25, 8(3652) 60-80-22 </p></bio><email xlink:type="simple">khalilov.edem@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Крымский федеральный университет им. В.И. Вернадского, Симферополь</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Crimean Federal University named after V.I. Vernadsky, Simferopol</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2018</year></pub-date><volume>10</volume><issue>4</issue><fpage>134</fpage><lpage>138</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Рымаренко Н.В., Бобрышева А.В., Крюгер Е.А., Халилов Э.Я., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Рымаренко Н.В., Бобрышева А.В., Крюгер Е.А., Халилов Э.Я.</copyright-holder><copyright-holder xml:lang="en">Rymarenko N.V., Bobrysheva A.V., Krjuger E.A., Halilov E.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.niidi.ru/jofin/article/view/814">https://journal.niidi.ru/jofin/article/view/814</self-uri><abstract><p>Рассмотрены клинические особенности дебюта и динамики гангренозной эктимы, протекающей с развитием сепсиса у ребенка 8 месяцев. Подробно описаны и представлены на рисунках кожные проявления заболевания в виде плотных геморрагических быстро расширяющихся папул с синюшным ореолом и развивающимся некрозом в центре элементов, с последующим формированием язв или пузырей. Диагноз устанавливался на основании клинических проявлений и высева Pseudomonas aeruginosa из содержимого пузырей и крови. Несмотря на проводимую интенсивную терапию и использование антибактериальных препаратов, обладающих антипсевдомонадной активностью, девочка умерла на 17-й день от момента госпитализации.</p></abstract><trans-abstract xml:lang="en"><p>The clinical features of the onset and dynamics of ecthyma gangrenosum caused by Pseudomonas aeruginosa with the development of sepsis are observed in an eight-monthold child. The article incudes a detailed description and corresponding photo images of skin manifestations of the disease in the form of solid hemorrhagic fast-growing papules with a cyanotic halo and developing necrosis in the centre of the elements followed by the formation of ulcers or blisters. The diagnosis was made on basis of clinical manifestations and Pseudomonas aeruginosa culture from the contents of the blisters and blood. In spite of being treated intensely and being given antibacterial preparations possessing anti-Pseudomonad activity, the girl died on the 17th day after hospitalization.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>синегнойная инфекция</kwd><kwd>гангренозная эктима</kwd><kwd>клинические симптомы</kwd><kwd>лечение</kwd><kwd>дети</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pseudomonas infection</kwd><kwd>ecthyma gangrenosum</kwd><kwd>clinical symptoms</kwd><kwd>treatment</kwd><kwd>infants</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Huang YC, Lin TY, Wang CH. Community-acquired Pseudomonas aeruginosa sepsis in previously healthy infants and children: analysis of forty-three episodes. Pediatr Infect Dis J. 2002;21:1049–52. DOI:10.1097/01.inf.0000036089.63240.37</mixed-citation><mixed-citation xml:lang="en">Huang YC, Lin TY, Wang CH. 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