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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">jofin</journal-id><journal-title-group><journal-title xml:lang="ru">Журнал инфектологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal Infectology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-6732</issn><publisher><publisher-name>IPO “АIDSSPbR"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22625/2072-6732-2017-9-4-119-125</article-id><article-id custom-type="elpub" pub-id-type="custom">jofin-664</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Эпидемиология</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Epidemiology</subject></subj-group></article-categories><title-group><article-title>ЭПИДЕМИОЛОГИЧЕСКАЯ ХАРАКТЕРИСТИКА ИНФЕКЦИИ, ВЫЗВАННОЙ ВИРУСОМ ГЕРПЕСА 2 ТИПА, В КРУПНОМ ЦЕНТРЕ АРКТИЧЕСКОЙ ЗОНЫ РОССИИ</article-title><trans-title-group xml:lang="en"><trans-title>EPIDEMIOLOGICAL CHARACTERISTIC OF HERPES SIMPLEX VIRUS TYPE 2 INFECTION AT A LARGE CENTER OF RUSSIAN ARCTIC ZONE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Балаева</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Balaeva</surname><given-names>T. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Балаева Татьяна Викторовна – врач-эпидемиолог,  аспирант кафедры общественного здоровья, здравоохранения и социальной работы.</p><p> </p></bio><bio xml:lang="en"><p>Arkhangelsk.</p></bio><email xlink:type="simple">arkhangelsk.tatiana@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Самодова</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Samodova</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Самодова Ольга Викторовна – заведующая кафедрой инфекционных болезней, доктор медицинских наук. </p><p>Архангельск.</p></bio><bio xml:lang="en"><p>Arkhangelsk.</p></bio><email xlink:type="simple">ovsamodova@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Санников</surname><given-names>А. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Sannikov</surname><given-names>A. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Санников Анатолий Леонидович – профессор кафедры общественного здоровья, здравоохранения  и социальной работы,  доктор медицинских наук. </p><p>Архангельск.</p></bio><bio xml:lang="en"><p>Arkhangelsk.</p></bio><email xlink:type="simple">jsannikov@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Центр гигиены и эпидемиологии в Архангельской области;  Северный государственный медицинский университет.</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Center of Hygiene and Epidemiology in Arkhangelsk region;  Northern State Medical University.</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Северный государственный медицинский университет.</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Northern State Medical University.</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>10</day><month>01</month><year>2018</year></pub-date><volume>9</volume><issue>4</issue><fpage>119</fpage><lpage>125</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Балаева Т.В., Самодова О.В., Санников А.Л., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Балаева Т.В., Самодова О.В., Санников А.Л.</copyright-holder><copyright-holder xml:lang="en">Balaeva T.V., Samodova O.V., Sannikov A.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.niidi.ru/jofin/article/view/664">https://journal.niidi.ru/jofin/article/view/664</self-uri><abstract><p>Во всем мире инфекция, вызванная вирусом простого герпеса 2 типа (ВПГ-2-инфекция), является одной из наиболее распространенных инфекций, передаваемых половым путем, и самой частой причиной язвенных поражений половых органов. В РФ эпидемиология ВПГ-2инфекции изучена недостаточно.</p><sec><title>Цель</title><p>Цель: определение распространенности ВПГ-2инфекции среди взрослого населения на Северо-Западе России (на примере г. Архангельска).</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы: исследование является частью Норвежско-Российского проекта и представляет собой популяционное поперечное исследование. Агентство социологических исследований проводило набор жителей г. Архангельска для участия в исследовании, используя целевые половозрастные показатели необходимого числа респондентов в каждом районе города. Лабораторное исследование крови на обнаружение иммуноглобулинов G к ВПГ-2 крови было проведено методом ИФА с использованием тест-систем фирмы «ВекторБест» (Новосибирск).</p></sec><sec><title>Результаты</title><p>Результаты: из 1243 респондентов 44% (543 человека) были мужчины, 56% (700 человек) – женщины, средний возраст составил 27,6 ±5,6 лет и 27,0 ±5,7 лет соответственно. Согласно лабораторным исследованиям, серопревалентность в выборке составила 18,8% (95% ДИ 16,8–21,1), при этом она была в 2 раза больше среди женщин во всех возрастных группах (24,0%, 95% ДИ 20,1–27,3 среди женщин и 12,2%, 95% ДИ 9,7–15,2 среди мужчин; p &lt; 0,001) . Доля серопозитивных лиц увеличивалась с возрастом как среди мужчин, так и среди женщин.</p></sec><sec><title>Заключение</title><p>Заключение: результаты проведенного исследования по изучению распространенности ВПГ-2-инфекции среди взрослого населения г. Архангельска подтверждают данные, полученные в европейских странах с высоким уровнем ее распространенности, а также в США. Высокая распространенность ВПГ-2-инфекции среди женщин в детородном возрасте показывает эпидемический потенциал ВПГ-2 при передаче от матери младенцам (вертикальный механизм передачи возбудителя). </p></sec></abstract><trans-abstract xml:lang="en"><p>Globally, infection caused by herpes simplex virus type 2 (HSV-2) is one of the most prevalent sexually transmitted infections and the most frequent cause of the genital ulcer diseases. The information about HSV-2 epidemiology in Russia is insufficient. Aim of the study: to define the prevalence of HSV-2 among general adult population in Northwest Russia (Arkhangelsk).</p><sec><title>Material and methods</title><p>Material and methods. The study was a part of a large Norwegian-Russian project and has a population-based cross-sectional design. The agency on social researches recruited residents of Arkhangelsk using a quota sampling method. The ELISA method was used to test the blood samples on Ig G g2; kits of Vector Best (Novosibirsk, Russia) were used.</p></sec><sec><title>Results</title><p>Results. Altogether, 1243 participants provided the blood samples and fulfilled the questionnaire. Men represented 44% (543 persons) and women – 56 (700 persons), the mean age was 27,6±5,6 and 27,0±5,7 years respectively. Seroprevalence of HSV-2 in the sample was 18,8% (95% CI 16,8– 21,1), seroprevalence among women was in 2 times higher compared with men (24,0%, 95% CI 20,1–27,3 and 12,2%, 95% CI 9,7–15,2 respectively; p&lt;0,001). The percentage of positive results increased with age in both men and women.</p></sec><sec><title>Conclusion</title><p>Conclusion. According to our data seroprevalence of HSV-2 among young adults in Arkhangelsk was comparable with seroprevalence in some European countries with high figures and with USA. High prevalence of HSV-2 among females in reproductive age shows the potential of this infection in vertical transmission.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>вирус простого герпеса 2 типа</kwd><kwd>ВПГ-2-инфекция</kwd><kwd>распространенность</kwd><kwd>популяционное исследование</kwd></kwd-group><kwd-group xml:lang="en"><kwd>virus of herpes simplex type 2</kwd><kwd>herpes simplex virus type 2 infection</kwd><kwd>prevalence</kwd><kwd>population-based study</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">. 1. Исаков, В.А. Герпесвирусные инфекции человека: руководство для врачей / В.А. Исаков, Е.И. Архипова, Д.В. Исаков ; под ред. В.А.Исакова. – СПб: СпецЛит, 2013. – 2-е изд. перераб. и доп. – 670 с.</mixed-citation><mixed-citation xml:lang="en">Isakov V.A., Arhipova E.I., Isakov D.V. 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