jofinЖурнал инфектологииJournal Infectology2072-6732IPO “АIDSSPbR"10.22625/2072-6732-2017-9-3-5-13jofin-626Research ArticleОбзорReviewОСТРЫЕ НЕЙРОИНФЕКЦИИ И СИМПТОМАТИЧЕСКАЯ ЭПИЛЕПСИЯ У ДЕТЕЙ: ПРИЧИННО-СЛЕДСТВЕННЫЕ СВЯЗИ (обзор литературы)ACUTE NEUROINFECTIONS AND SYMPTOMATIC EPILEPSY IN CHILDREN: CAUSAL RELATIONSHIP (review)ГореликЕ. Ю.GorelikE. Yu.e.gorelik@mail.ruВойтенковВ. Б.VoitenkovV. B.vlad203@inbox.ruСкрипченкоН. В.SkripchenkoN. V.snv@niidi.ruВильницА. А.VilnitsA. A.vilnitz@mail.ruИвановаМ. В.IvanovaM. V.doctor-ivanova@yandex.ruКлимкинА. В.KlimkinA. V.klinkinpark@mail.ruДетский научно-клинический центр инфекционных болезнейРоссияPediatric Research and Clinical Center for Infectious DiseasesRussian FederationДетский научно-клинический центр инфекционных болезней; Санкт-Петербургский государственный педиатрический медицинский университетРоссияPediatric Research and Clinical Center for Infectious Diseases; Saint-Petersburg State Pediatric Medical UniversityRussian Federation20171210201793513Copyright © Горелик Е.Ю., Войтенков В.Б., Скрипченко Н.В., Вильниц А.А., Иванова М.В., Климкин А.В., 20172017Горелик Е.Ю., Войтенков В.Б., Скрипченко Н.В., Вильниц А.А., Иванова М.В., Климкин А.В.Gorelik E.Y., Voitenkov V.B., Skripchenko N.V., Vilnits A.A., Ivanova M.V., Klimkin A.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://journal.niidi.ru/jofin/article/view/626

Судороги при острых нейроинфекциях у детей могут как осложнять течение заболевания, так и трансформироваться в симптоматическую эпилепсию, являющуюся важнейшей медико-социальной проблемой. В обзорной статье представлены сведения об эпидемиологии судорожного синдрома и симптоматической эпилепсии при нейроинфекциях у детей. Рассмотрены современные иммуно-биохимические аспекты эпилептогенеза при инфекционной патологии. Отражены сведения о нейрофизиологических и лучевых особенностях при симптоматической эпилепсии, развившейся при нейроинфекциях различной этиологии. Сделан акцент на практической значимости своевременной комплексной этио-патогенетической терапии нейроинфекций, осложненных развитием судорожного синдрома, что позволяет снизить частоту развития симптоматической эпилепсии. Представлены сведения о результатах применения транскраниальной магнитной стимуляции при рефрактерной эпилепсии.

Convulsions in case of acute neuroinfections can both complicate the disease course and transfer to symptomatic epilepsy which is one of the most important medical and social problems. The review article presents the data on epidemiology of convulsive disorder and symptomatic epilepsy in case of neuroinfections in children. There are considered the current immune and biochemical aspects of epileptogenesis in case of infectious pathology. There is given the information on neurophysiological and radial features of symptomatic epilepsy developed in case of neuroinfections of different etiology. There is underlined the practical significance of timely complex etio-pathogenetic therapy for neuroinfections complicated by convulsion that allows to reduce the frequency of symptomatic epilepsy development. There are presented the data on the results of transcranial magnetic stimulation in case of refractory epilepsy.

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The authors declare that there are no conflicts of interest present.