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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">jofin</journal-id><journal-title-group><journal-title xml:lang="ru">Журнал инфектологии</journal-title><trans-title-group xml:lang="en"><trans-title>Journal Infectology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-6732</issn><publisher><publisher-name>IPO “АIDSSPbR"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22625/2072-6732-2011-3-3-52-55</article-id><article-id custom-type="elpub" pub-id-type="custom">jofin-41</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Оригинальные исследования</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Original Research</subject></subj-group></article-categories><title-group><article-title>Justification of the program therapy of acute hepatitis C</article-title><trans-title-group xml:lang="en"><trans-title>Justification of the program therapy of acute hepatitis C</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Михайлова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mikhailova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доцент кафедры инфекционных болезней Нижегородской государственной медицинской академии, к.м.н.; тел.: 8(831)433-44-46</p></bio><email xlink:type="simple">mikhailov-leto@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соболевская</surname><given-names>О. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Sobolevskaya</surname><given-names>O. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доцент кафедры инфекционных болезней Нижегородской государственной медицинской академии, к.м.н.; тел.: 8-910-396-91-37</p></bio><email xlink:type="simple">vad5584@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Нижегородская государственная медицинская академия, Нижний Новгород</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Nizhegorodskaya State Medical Academy, Nizhniy Novgorod</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>06</day><month>09</month><year>2014</year></pub-date><volume>3</volume><issue>3</issue><fpage>52</fpage><lpage>55</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Михайлова Е.А., Соболевская О.Л., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Михайлова Е.А., Соболевская О.Л.</copyright-holder><copyright-holder xml:lang="en">Mikhailova E.A., Sobolevskaya O.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://journal.niidi.ru/jofin/article/view/41">https://journal.niidi.ru/jofin/article/view/41</self-uri><abstract><p>Treatment of acute hepatitis C remains one of the main problems of modern hepatology. There are many variants of treatment, but there is no common opinion about scheme and time of onset of the therapy. From the other hand, early treatment can prevent chronisation in more than 70% of cases. Specific therapy was used 135 patients with acute hepatitis C aged from 16 to 52 years (26,5+0,7 years). Our analysis has shown, that its better to start specific therapy on the second month of the disease with -interferon monotherapy by induction scheme.</p></abstract><trans-abstract xml:lang="en"><p>Treatment of acute hepatitis C remains one of the main problems of modern hepatology. There are many variants of treatment, but there is no common opinion about scheme and time of onset of the therapy. From the other hand, early treatment can prevent chronisation in more than 70% of cases. Specific therapy was used 135 patients with acute hepatitis C aged from 16 to 52 years (26,5+0,7 years). Our analysis has shown, that its better to start specific therapy on the second month of the disease with -interferon monotherapy by induction scheme.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>acute hepatitis C</kwd><kwd>antiviral therapy</kwd><kwd>induction treatment scheme</kwd></kwd-group><kwd-group xml:lang="en"><kwd>acute hepatitis C</kwd><kwd>antiviral therapy</kwd><kwd>induction treatment scheme</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Jackel, E. The course and therapy of acute hepatitis C viral infection. Is a prevention of its becoming chronic possible? / . Jackel, M.P. Manns // Z. Gastroenterol. – 2000. – № 38. – P. 387–395.</mixed-citation><mixed-citation xml:lang="en">Jackel, E. The course and therapy of acute hepatitis C viral infection. Is a prevention of its becoming chronic possible? / . Jackel, M.P. Manns // Z. 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